Risberg A, Larsson A, Bodén U, Edner A
Department of Health, Education and Technology, Lulea University of Technology, Lulea, S-971 87, Sweden.
Department Medical Sciences, Clinical Chemistry, Academic Hospital, Uppsala, S- 75185, Sweden.
BMC Complement Med Ther. 2025 Sep 8;25(1):327. doi: 10.1186/s12906-025-05076-6.
There has been growing interest in animal-assisted therapy (AAT) in recent decades due to increasing reports indicating its health benefits for adult patients. These benefits are partly attributed to changes, usually increased levels of the neuropeptide oxytocin. AIM: To investigate changes in oxytocin levels in hospitalized children meeting a certified Hospital Dog.
Urine samples were collected between 25/02/2016 and 24/05/2017 from 35 hospitalized children (3-17 years) before and after each participant had a session with the Hospital Dog. Oxytocin levels were analysed with an acetylcholinesterase (AChE) competitive enzyme-linked immunosorbent assay (ELISA). Creatinine levels were measured to determine the subject's fluid intake and then divided by the hormonal concentration (uOT pg/ml).
The mean level of uOT was 186.0 ± 236.7 (51.5-1349.5) pg/ml before and 137.3 ± 121.5 (30.7-591.3) pg/ml after the dog session (p = 0.010).
Decreased levels of uOT were recorded during the study in which hospitalized children met a Hospital Dog. The decreased OT levels are potentially the result of the intense activity the subject experienced with the dog during the interaction.
近几十年来,动物辅助疗法(AAT)越来越受到关注,因为越来越多的报告表明其对成年患者有益健康。这些益处部分归因于变化,通常是神经肽催产素水平的升高。目的:研究与经过认证的医院犬接触的住院儿童体内催产素水平的变化。
在2016年2月25日至2017年5月24日期间,收集了35名住院儿童(3至17岁)在与医院犬每次接触前后的尿液样本。采用乙酰胆碱酯酶(AChE)竞争性酶联免疫吸附测定(ELISA)分析催产素水平。测量肌酐水平以确定受试者的液体摄入量,然后除以激素浓度(uOT pg/ml)。
与犬接触前,uOT的平均水平为186.0±236.7(51.5 - 1349.5)pg/ml,接触后为137.3±121.5(30.7 - 591.3)pg/ml(p = 0.010)。
在该研究中,与医院犬接触的住院儿童体内uOT水平下降。催产素水平下降可能是受试者在互动过程中与犬剧烈活动的结果。