Yamamoto Yohei, Tsukuda Kazuki, Kazama Ai, Wada Yoshiki, Kikuchi Toru, Ichinose Tsuyoshi, Kudo Toshifumi
Division of Vascular Surgery, Department of Cardiovascular Surgery, Institute of Science Tokyo, Tokyo, Japan.
Medicine (Baltimore). 2025 Sep 5;104(36):e44346. doi: 10.1097/MD.0000000000044346.
Polycythemia vera (PV) is a type of myeloproliferative disorder, and thrombosis is one of its important complications. Arterial thrombosis commonly occurs in the coronary and cerebral arteries; however, reports of thrombosis in other arteries are limited, and it is even rarer in visceral arteries.
A 50-year-old woman with PV presented with anorexia and epigastric pain. Detailed history taking revealed a 2-year history of postprandial abdominal pain.
Enhanced computed tomography revealed severe stenosis of the celiac artery and thrombotic occlusion of the common hepatic, splenic, and superior mesenteric arteries. The patient was diagnosed with chronic mesenteric ischemia.
The patient underwent an infrarenal aorta-to-superior mesenteric artery bypass using a great saphenous vein graft.
The postoperative course was uneventful, and her gastrointestinal symptoms resolved completely.
The present case highlights that a patient with PV can develop symptomatic visceral arterial thrombosis. Open mesenteric bypass surgery effectively relieved symptoms.
真性红细胞增多症(PV)是一种骨髓增殖性疾病,血栓形成是其重要并发症之一。动脉血栓形成通常发生在冠状动脉和脑动脉;然而,关于其他动脉血栓形成的报道有限,在内脏动脉中更为罕见。
一名50岁的PV女性患者出现厌食和上腹部疼痛。详细的病史询问显示有2年的餐后腹痛病史。
增强计算机断层扫描显示腹腔动脉严重狭窄,肝总动脉、脾动脉和肠系膜上动脉血栓闭塞。该患者被诊断为慢性肠系膜缺血。
患者接受了使用大隐静脉移植物的肾下腹主动脉至肠系膜上动脉旁路移植术。
术后过程顺利,她的胃肠道症状完全缓解。
本病例强调PV患者可发生有症状的内脏动脉血栓形成。开放性肠系膜旁路手术有效缓解了症状。