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预防青少年自杀念头和行为:应对能力预防干预交叉影响的综合数据分析

Preventing Suicidal Thoughts and Behaviors Among Youth: Integrative Data Analysis of Crossover Impacts of the Coping Power Preventive Intervention.

作者信息

McDaniel Heather L, Budavari Alexa C, Tonigan Alexandra, Michael Ava E, West Stephen G, O'Shea Nisha Gottfredson, Powell Nicole P, Qu Lixin, Saavedra Lissette M, Yaros Anna, Bradshaw Catherine P, Lochman John E, Morgan-López Antonio A

机构信息

University of South Carolina, Columbia, South Carolina.

University of Virginia, Charlottesville, Virginia.

出版信息

JAACAP Open. 2025 Feb 7;3(3):467-476. doi: 10.1016/j.jaacop.2025.01.005. eCollection 2025 Sep.

Abstract

OBJECTIVE

Despite evidence-based interventions for psychiatric disorders that often precede suicidality, suicide remains a leading cause of death among youth. There has been increased interest in whether preventive interventions targeting early risk factors lead to decreased distal risk for suicidal thoughts and behaviors (STBs). This study examined the impact of Coping Power (CP), a school-based preventive intervention targeting externalizing problems, on STBs.

METHOD

The sample included 3,182 youths (36.4% female; 77.3% Black) who participated in 1 of 11 randomized controlled trials of CP. Individual-level data across trials were harmonized using integrative data analysis to address cross-study variation in measurement of STBs. The study used meta-analysis of individual participant data for modeling cross-study variation in intervention effects and propensity score weighting for addressing covariate imbalance arising from combining intervention arms across studies. Hypothesis tests were conducted for parent- and teacher-reported STBs under propensity score-weighted multilevel modeling.

RESULTS

Compared with school as usual, youth participating in mindfulness-enhanced CP demonstrated significant decreases in parent-reported STBs over time ( = -.08 [.02], < .001; after 1 year: = -0.13; after 2 years: = -0.25), and youth participating in Internet-enhanced CP demonstrated significant decreases in teacher-reported STBs over time ( = -.08 [.03], = .003; after 1 year: = -0.20; after 2 years: = -0.40). Inconsistent results for standard CP and individual CP in sensitivity analyses preclude clear conclusions for these 2 intervention formats.

CONCLUSION

Synthesis of the reported findings highlights the promise of digital health and mindfulness-based interventions for youth with externalizing problems in reducing STBs. Additional research is needed to better understand the nature of for whom, how, and under what conditions preventive interventions impact later STBs.

DIVERSITY & INCLUSION STATEMENT: We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. One or more of the authors of this paper self-identifies as living with a disability. One or more of the authors of this paper received support from a program designed to increase minority representation in science. We actively worked to promote sex and gender balance in our author group. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list.

摘要

目的

尽管针对精神疾病的循证干预措施常常先于自杀行为出现,但自杀仍是青少年死亡的主要原因。针对早期风险因素的预防性干预措施是否会降低自杀念头和行为(STB)的远期风险,这一问题已引发越来越多的关注。本研究考察了应对能力(CP)这一针对外化问题的校内预防性干预措施对STB的影响。

方法

样本包括3182名青少年(36.4%为女性;77.3%为黑人),他们参与了CP的11项随机对照试验中的1项。通过整合数据分析对各试验的个体层面数据进行协调,以解决STB测量中的跨研究差异。该研究使用个体参与者数据的荟萃分析来模拟干预效果的跨研究差异,并使用倾向得分加权来解决因合并各研究中的干预组而产生的协变量不平衡问题。在倾向得分加权的多层模型下,对家长和教师报告的STB进行了假设检验。

结果

与常规学校教育相比,参与正念增强型CP的青少年,家长报告的STB随时间显著减少(β = -.08 [.02],p <.001;1年后:β = -0.13;2年后:β = -0.25),参与网络增强型CP的青少年,教师报告的STB随时间显著减少(β = -.08 [.03],p =.003;1年后:β = -0.20;2年后:β = -0.40)。敏感性分析中标准CP和个体CP的结果不一致,无法对这两种干预形式得出明确结论。

结论

综合报告的研究结果凸显了数字健康和基于正念的干预措施对于有外化问题的青少年在减少STB方面的前景。需要更多研究来更好地理解预防性干预措施对哪些人、如何以及在何种条件下会影响后期的STB。

多样性与包容性声明

我们努力确保在招募人类参与者时实现性别平衡。我们努力确保在招募人类参与者时实现种族、民族和/或其他类型的多样性。我们努力确保研究问卷以包容性方式编制。本文的一位或多位作者自我认同为科学领域中一个或多个历史上代表性不足的种族和/或民族群体的成员。本文的一位或多位作者自我认同为科学领域中一个或多个历史上代表性不足的性取向和/或性别群体的成员。本文的一位或多位作者自我认同为残疾人士。本文的一位或多位作者获得了旨在增加科学领域中少数群体代表性的项目的支持。我们积极努力促进作者群体中的性别平衡。我们积极努力促进作者群体中纳入科学领域中历史上代表性不足的种族和/或民族群体。本文的作者名单包括来自研究开展地点和/或社区的贡献者,他们参与了数据收集、设计、分析和/或对工作的解释。在引用与本工作科学相关的参考文献时,我们也积极努力促进作者群体中纳入科学领域中历史上代表性不足的种族和/或民族群体。在引用与本工作科学相关的参考文献时,我们也积极努力促进参考文献列表中的性别平衡。

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