Combs Jennifer, Lin Ping-I, DelBello Melissa P, Carle Adam C, Bridge Jeffrey A, Axelson David A, Fornari Victor, Feuer Vera, Emslie Graham J, Kennard Betsy D, Porter Stephen C, Sorter Michael T, Barzman Drew
Cincinnati Children's Hospital, Cincinnati, Ohio.
Saint Louis University School of Medicine, St. Louis Missouri, and the University of New South Wales, Australia.
JAACAP Open. 2024 Nov 8;3(3):567-575. doi: 10.1016/j.jaacop.2024.10.005. eCollection 2025 Sep.
Suicide is a leading cause of death for adolescents in the United States. Alternative settings to treat suicidal ideation (SI) are needed. Study primary objectives include evaluating the safety and effectiveness of telehealth crisis intervention services (CIS) and in-person outpatient crisis intervention clinics (OCIC) relative to the current standard of care of inpatient psychiatric hospitalization. A secondary aim seeks to assess changes in suicidal ideation, and patient and parent treatment satisfaction.
The study team, consisting of study staff at 4 sites, conducted an observational longitudinal study of patients (12-18 years of age) who were seen in the Emergency Department (ED) for suicidality and were referred to inpatient treatment, in-person OCIC, or telehealth CIS. Primary outcome data, including recurrent ED visits and hospitalizations because of SI, suicide attempts, and life satisfaction, were collected for 24 weeks. All analyses were adjusted for age, sex, and baseline suicidality severity scores. A total of 249 patients were enrolled.
There were no statistically significant differences in suicide attempts, time to first suicide attempt, ED visits, hospitalizations, and life satisfaction among the 3 treatment arms. There was no statistically significant difference in outcomes for treatment satisfaction among the treatment groups.
In this observational study, in-person OCIC and telehealth CIS did not have significantly different outcomes from the current standard of care of inpatient psychiatric hospitalization. This broadens the scope of services that appear to be safe and effective for adolescents experiencing moderate suicidal thoughts. Future research using randomized controlled trials to clarify the causal effect of different interventions is warranted.
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents (Pre-START); https://clinicaltrials.gov/study/NCT04625686.
We worked to ensure that the study questionnaires were prepared in an inclusive way. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.
自杀是美国青少年的主要死因。需要有替代环境来治疗自杀意念(SI)。研究的主要目标包括评估远程医疗危机干预服务(CIS)和面对面门诊危机干预诊所(OCIC)相对于目前住院精神科治疗这一标准治疗方法的安全性和有效性。次要目标是评估自杀意念的变化以及患者和家长对治疗的满意度。
由4个地点的研究人员组成的研究团队,对因自杀倾向在急诊科(ED)就诊并被转诊至住院治疗、面对面OCIC或远程医疗CIS的12至18岁患者进行了一项观察性纵向研究。收集了24周的主要结局数据,包括因自杀意念导致的再次急诊就诊和住院、自杀未遂以及生活满意度。所有分析均根据年龄、性别和基线自杀倾向严重程度评分进行了调整。共招募了249名患者。
三个治疗组在自杀未遂、首次自杀未遂时间、急诊就诊、住院和生活满意度方面没有统计学上的显著差异。治疗组之间在治疗满意度结局方面也没有统计学上的显著差异。
在这项观察性研究中,面对面OCIC和远程医疗CIS与目前住院精神科治疗的标准治疗方法相比,结局没有显著差异。这拓宽了对于有中度自杀想法的青少年而言似乎安全有效的服务范围。有必要开展未来的随机对照试验研究以阐明不同干预措施的因果效应。
比较自杀青少年不同精神科治疗结局的观察性研究(START前);https://clinicaltrials.gov/study/NCT04625686。
我们努力确保研究问卷以包容性方式编制。本文作者名单包括研究开展地点和/或社区参与数据收集、设计、分析和/或工作解读的贡献者。