Selvaraj Mughilan, Kumar Prasanna, Balakrishnan S, Selvaraj Karthikeyan, Yesuvadiyan Jesu Pencilin
General Surgery, Sree Balaji Medical College and Hospital, Chennai, IND.
Cureus. 2025 Aug 7;17(8):e89545. doi: 10.7759/cureus.89545. eCollection 2025 Aug.
Gas gangrene is a rare, life-threatening infection caused mainly by and other species, such as , , , and . Other microbial pathogens also reported to cause gas gangrene are and . It is fulminant and associated with high rates of morbidity and mortality, especially in patients with underlying comorbidities such as diabetes mellitus. Major underlying etiology is associated with a history of trauma or surgical wounds exposed to soil and fecal matter containing the causative microbes. This is a case of a 53-year-old man with unmanaged diabetes presenting with gas gangrene in his right lower limb. He was managed by below-knee amputation. The histopathological analysis confirmed as the causative organism.
气性坏疽是一种罕见的、危及生命的感染,主要由产气荚膜梭菌及其他梭菌属物种引起,如败毒梭菌、诺维梭菌、溶组织梭菌和双酶梭菌。其他据报道可引起气性坏疽的微生物病原体有产气芽孢杆菌和腐败芽孢杆菌。它发展迅猛,与高发病率和死亡率相关,尤其是在患有如糖尿病等基础合并症的患者中。主要潜在病因与创伤史或暴露于含有致病微生物的土壤和粪便物质的手术伤口有关。这是一例53岁未控制糖尿病的男性患者,其右下肢出现气性坏疽。他接受了膝下截肢治疗。组织病理学分析证实产气荚膜梭菌为致病微生物。