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[胆肠吻合术:技术与结果]

[Biliodigestive anastomosis: technique and outcome].

作者信息

Brunner Maximilian, Grützmann Robert

机构信息

Klink für Allgemein- und Viszeralchirurgie, Universitätsklinikum der Friedrich-Alexander-Universität Erlangen, Erlangen, Deutschland.

, Krankenhausstr. 12, 91054, Erlangen, Deutschland.

出版信息

Chirurgie (Heidelb). 2025 Sep 9. doi: 10.1007/s00104-025-02372-2.

DOI:10.1007/s00104-025-02372-2
PMID:40924083
Abstract

The biliodigestive anastomosis represents a core element of hepatopancreatobiliary surgery. It requires a precise surgical technique and detailed knowledge of biliary anatomy and vascular supply. A tension-free suture, sufficient perfusion of the anastomosed structures and an exact mucosa-to-mucosa adaptation using delicate absorbable suture material are decisive for a successful construction. Hepaticojejunostomy has become established as the gold standard for a biliodigestive anastomosis. Currently available studies show no significant differences in morbidity between open and minimally invasive techniques, whereby the latter is becoming increasingly more important. There was also no difference in the clinical results with respect to the suture technique (interrupted vs. continuous suture); however, the continuous suture technique is associated with a shortening of the placement time and a reduction in costs. Complications after biliodigestive anastomosis, such as insufficiency and stenosis, are clinically relevant and substantially influence the morbidity and mortality; however, many of these complications can nowadays be effectively treated by interventional procedures.

摘要

胆肠吻合术是肝胰胆外科手术的核心组成部分。它需要精确的手术技巧以及对胆道解剖结构和血管供应的详细了解。无张力缝合、吻合结构的充分灌注以及使用精细可吸收缝合材料实现精确的黏膜对黏膜贴合,对于成功构建吻合至关重要。肝空肠吻合术已成为胆肠吻合术的金标准。目前的研究表明,开放手术和微创技术在发病率方面无显著差异,而微创技术正变得越来越重要。在缝合技术(间断缝合与连续缝合)方面,临床结果也没有差异;然而,连续缝合技术可缩短缝合时间并降低成本。胆肠吻合术后的并发症,如吻合口漏和狭窄,具有临床相关性,并对发病率和死亡率有重大影响;然而,如今许多此类并发症可通过介入治疗得到有效处理。

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本文引用的文献

1
The impact of vascular injuries on the management of bile duct injury following laparoscopic cholecystectomy- insights from a prospective study.血管损伤对腹腔镜胆囊切除术后胆管损伤处理的影响——一项前瞻性研究的见解
HPB (Oxford). 2025 Apr;27(4):544-552. doi: 10.1016/j.hpb.2024.12.022. Epub 2025 Jan 6.
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Continuous or Interrupted Suture for Hepaticojejunostomy in Pancreaticoduodenectomy (The HEKTIK Trial): Findings of a Randomized, Controlled, Single-Center Superiority Trial.胰十二指肠切除术中肝空肠吻合术的连续或间断缝合(HEKTIK试验):一项随机、对照、单中心优效性试验的结果
Dtsch Arztebl Int. 2024 Oct 18;121(21):696-702. doi: 10.3238/arztebl.m2024.0178.
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Comparison of short-term outcomes of robotic versus open pancreaticoduodenectomy: a meta-analysis of randomized controlled trials and propensity-score-matched studies.
机器人辅助与开放胰十二指肠切除术短期结局的比较:一项随机对照试验和倾向评分匹配研究的荟萃分析
Int J Surg. 2025 Jan 1;111(1):1214-1230. doi: 10.1097/JS9.0000000000001871.
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Effect of robotic versus open pancreaticoduodenectomy on postoperative length of hospital stay and complications for pancreatic head or periampullary tumours: a multicentre, open-label randomised controlled trial.机器人与开腹胰十二指肠切除术对胰头或壶腹周围肿瘤术后住院时间和并发症的影响:一项多中心、开放标签随机对照试验。
Lancet Gastroenterol Hepatol. 2024 May;9(5):428-437. doi: 10.1016/S2468-1253(24)00005-0. Epub 2024 Feb 28.
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Robotic versus open partial pancreatoduodenectomy (EUROPA): a randomised controlled stage 2b trial.机器人辅助与开放部分胰十二指肠切除术(EUROPA):一项随机对照2b期试验
Lancet Reg Health Eur. 2024 Feb 22;39:100864. doi: 10.1016/j.lanepe.2024.100864. eCollection 2024 Apr.
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Comparison of Surgical Outcomes of Laparoscopic and Robotic Surgery in Adult Choledochal Cysts.成人胆总管囊肿腹腔镜与机器人手术治疗效果的比较。
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Innovative suture technique for robotic hepaticojejunostomy: double-layer interrupted sutures.创新的机器人胆肠吻合缝合技术:双层间断缝合。
Langenbecks Arch Surg. 2023 Jul 20;408(1):284. doi: 10.1007/s00423-023-03020-1.
8
Interrupted versus continuous suture technique for biliary-enteric anastomosis: randomized clinical trial.间断与连续缝合技术在胆肠吻合术中的随机临床试验。
BJS Open. 2023 Jan 6;7(1). doi: 10.1093/bjsopen/zrac163.
9
Outcomes of double-layer continuous suture hepaticojejunostomy in pancreatoduodenectomy and total pancreatectomy.胰十二指肠切除术和全胰切除术中行双层连续缝合胆肠吻合术的效果。
HPB (Oxford). 2022 Oct;24(10):1738-1747. doi: 10.1016/j.hpb.2022.05.005. Epub 2022 May 17.
10
Economics and safety of continuous and interrupted suture hepaticojejunostomy: An audit of 556 surgeries.连续缝合与间断缝合肝空肠吻合术的经济学与安全性:556例手术的审计
Ann Hepatobiliary Pancreat Surg. 2021 Nov 30;25(4):472-476. doi: 10.14701/ahbps.2021.25.4.472.