Chau Sek Hung, Elders Petra J M, Domić Jacintha, Nelissen-Vrancken H J Marjorie G, Schellevis François G, Hugtenburg Jacqueline G
Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands.
Int J Clin Pharm. 2025 Sep 8. doi: 10.1007/s11096-025-01992-2.
Organisational problems still prevent widespread implementation of clinical medication reviews. The Opti-Med2 method was developed to facilitate the process of performing clinical medication reviews. The method includes patient involvement by means of a questionnaire and expert teams of community pharmacists and general practitioners (GPs) to perform pharmacotherapeutic analyses, providing the patients' own GP with pharmacotherapeutic advice. There is a supporting role of community pharmacy technicians and general practice nurses/assistants in the process.
To gain insight into the implementation of the Opti-Med2 method within the framework of pharmacotherapeutic audit meeting groups in the Netherlands.
A mixed-methods implementation study in seven groups of primary care healthcare providers. Quantitative data were collected using study forms. Semi-structured interviews with 8 GPs, 5 community pharmacists and 2 community pharmacy technicians were held. Interviews were transcribed verbatim and were analysed using the extended Normalization Process Theory.
Only one group provided sufficient quantitative data for analysis. Of the pharmacotherapeutic advice given by the expert team, 72% was adopted by the GPs of which 85% resulted in an intervention with the patient. In general, the healthcare providers were satisfied with using the Opti-Med2 method. The use of expert teams was appreciated by most GPs and community pharmacists. All healthcare providers were very satisfied with the use of the patient questionnaire.
Although full implementation of Opti-Med2 method as a whole was not achieved, the structured organisation of conducting CMRs and the use of questionnaires was deemed successful.
组织层面的问题仍然阻碍着临床用药评估的广泛实施。Opti-Med2方法的开发旨在促进临床用药评估过程。该方法包括通过问卷让患者参与，以及由社区药剂师和全科医生（GP）组成的专家团队进行药物治疗分析，为患者自己的全科医生提供药物治疗建议。社区药房技术人员和全科医疗护士/助理在此过程中发挥辅助作用。
深入了解Opti-Med2方法在荷兰药物治疗审核会议小组框架内的实施情况。
对七组初级医疗保健提供者进行混合方法实施研究。使用研究表格收集定量数据。对8名全科医生、5名社区药剂师和2名社区药房技术人员进行了半结构化访谈。访谈内容逐字记录，并使用扩展的标准化过程理论进行分析。
只有一组提供了足够的定量数据用于分析。专家团队给出的药物治疗建议中，72%被全科医生采纳，其中85%导致了对患者的干预。总体而言，医疗保健提供者对使用Opti-Med2方法感到满意。大多数全科医生和社区药剂师赞赏使用专家团队。所有医疗保健提供者对使用患者问卷非常满意。
虽然Opti-Med2方法作为一个整体并未完全实施，但进行临床用药评估的结构化组织和问卷的使用被认为是成功的。
