Carlozzi Noelle E, Graves Christopher M, Freeman Jacqueline L, Leggett Amanda N, Miner Jennifer A, Lai Jin-Shei, Fansher Madison, Patel Minal R
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, Michigan, United States of America.
Department of Surgery, University of Michigan, Ann Arbor, Michigan, United States of America.
PLoS One. 2025 Sep 9;20(9):e0331114. doi: 10.1371/journal.pone.0331114. eCollection 2025.
Financial hardship (including financial stress, financial strain, asset depletion, and financial toxicity) is a highly relevant construct among the 6.9 million people living with Alzheimer's disease and related dementias (ADRD) in the United States and their family networks. This scoping review will identify existing measures and approaches for capturing financial strain among these families.
This scoping review will be reported in accordance with PRISMA-ScR guidelines. Searches will be conducted in Embase (Embase.com), Medline (Ovid), CINAHLComplete (EbscoHost), AgeLine (EbscoHost), APA PsycInfo (EbscoHost), Scopus, and Web of Science Core Collection databases to identify tools, measures, or approaches for measuring self-reported financial hardship among family members of people living with ADRD. Data elements from both the National Health and Aging Trends Study and the associated National Study of Caregiving will also be considered. Two independent raters will screen the search results and discrepancies with be resolved by a third rater. Extraction will include the use of artificial intelligence-based software and verification by an independent human rater; any changes that are made to the AI-generated extraction will be reviewed by a second independent rater. A frequency analysis will be conducted to analyze the data, and a summary of the psychometric properties of each of the identified measures will be presented.
The findings from this review will be disseminated through peer-reviewed publications and conference presentations. Ultimately, this work will inform the development of a new patient-reported outcome measurement system designed to provide a comprehensive assessment of the different aspects of financial hardship for families of people living with ADRD.
In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P), the following protocol was registered via https://osf.io on March 14, 2025 (registration DOI: https://doi.org/10.17605/OSF.IO/J26KT).
在美国，690万患有阿尔茨海默病及相关痴呆症（ADRD）的患者及其家庭网络中，经济困难（包括经济压力、经济紧张、资产耗尽和经济毒性）是一个高度相关的概念。本范围综述将确定用于捕捉这些家庭经济紧张状况的现有措施和方法。
本范围综述将按照PRISMA-ScR指南进行报告。将在Embase（Embase.com）、Medline（Ovid）、CINAHL Complete（EbscoHost）、AgeLine（EbscoHost）、APA PsycInfo（EbscoHost）、Scopus和Web of Science核心合集数据库中进行检索，以识别用于测量ADRD患者家庭成员自我报告的经济困难的工具、措施或方法。还将考虑来自国家健康与老龄化趋势研究以及相关的国家护理研究中的数据元素。两名独立评估人员将筛选检索结果，如有分歧将由第三名评估人员解决。提取将包括使用基于人工智能的软件并由独立的人工评估人员进行验证；对人工智能生成的提取内容所做的任何更改将由第二名独立评估人员进行审核。将进行频率分析以分析数据，并呈现所识别的每项措施的心理测量特性总结。
本综述的结果将通过同行评审出版物和会议报告进行传播。最终，这项工作将为开发一种新的患者报告结局测量系统提供信息，该系统旨在全面评估ADRD患者家庭经济困难的不同方面。
根据系统评价和Meta分析方案的首选报告项目（PRISMA-P），以下方案于2025年3月14日通过https://osf.io进行了注册（注册DOI：https://doi.org/10.17605/OSF.IO/J26KT）。
