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退行性腰椎管狭窄症失代偿:患者需要立即手术吗?

Decompensation of degenerative lumbar stenosis: do patients need immediate surgery?

作者信息

Duigou Marie, Terrier Louis-Marie, Planty-Bonjour Alexia, Destrieux Christophe, Zemmoura Ilyess, François Patrick, Aggad Mourad, Amelot Aymeric

机构信息

Centre Hospitalier Régional Universitaire de Brest, Brest, France.

Hôpital privé Clairval, Marseille, France.

出版信息

Eur Spine J. 2025 Sep 11. doi: 10.1007/s00586-025-09272-3.

Abstract

PURPOSE

Degenerative lumbar spinal stenosis (DLSS) represents an increasing challenge due to the aging population. The natural course of untreated DLSS is largely unknown. For the acute DLSS decompensations, the main concern remains the opportunity and timing of surgery, i.e. does emergency decompression improve the neurological prognosis? This question continues to be controversial, and we've tried to clarify it.

METHODS

We conducted a retrospective analysis of 85 consecutive patients who underwent surgery for decompensated DLSS between January 2020 and 2024.

RESULTS

All patients presented with motor deficit (84.7%) and/or genital-sphincter dysfunction (25.9%). Surgical procedures included decompression alone (77.6%), decompression with discectomy (18.8%), or decompression with arthrodesis (3.5%). Complete neurological recovery was observed in 53 patients (62.4%) by the first follow-up visit (mean 4.6 months), while 32 patients (37.6%) had persistent neurological sequelae at final FU (mean 11.8 months). No significant association was found between neurological recovery and surgical timing, regardless of intervention within 48 h (p = 0.529), 7 days (p = 0.391), 15 days (p = 0.213), or 1 month (p = 0.435). Additionally, neither the degree of stenosis on MRI (p = 0.147), initial deficit severity (p = 0.06), patient age (p = 0.410), nor number of muscles involved (p = 0.328) were significantly associated with recovery.

CONCLUSION

Our findings suggest that urgent surgical intervention for decompensated DLSS does not significantly improve neurological outcomes.

摘要

目的

由于人口老龄化,退行性腰椎管狭窄症(DLSS)带来的挑战日益增加。未经治疗的DLSS的自然病程在很大程度上尚不清楚。对于急性DLSS失代偿,主要关注点仍然是手术时机,即急诊减压是否能改善神经预后?这个问题一直存在争议,我们试图对此进行阐明。

方法

我们对2020年1月至2024年期间连续85例行DLSS失代偿手术的患者进行了回顾性分析。

结果

所有患者均出现运动功能障碍(84.7%)和/或生殖括约肌功能障碍(25.9%)。手术方式包括单纯减压(77.6%)、减压联合椎间盘切除术(18.8%)或减压联合关节融合术(3.5%)。首次随访(平均4.6个月)时,53例患者(62.4%)神经功能完全恢复,而32例患者(37.6%)在末次随访(平均11.8个月)时仍有持续性神经后遗症。无论在48小时内(p = 0.529)、7天内(p = 0.391)、15天内(p = 0.213)还是1个月内(p = 0.435)进行干预,神经恢复与手术时机之间均未发现显著关联。此外,MRI上的狭窄程度(p = 0.147)、初始功能障碍严重程度(p = 0.06)、患者年龄(p = 0.410)或受累肌肉数量(p = 0.328)与恢复均无显著关联。

结论

我们的研究结果表明,对失代偿性DLSS进行紧急手术干预并不能显著改善神经功能结局。

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