Kleemann Thomas, Zahn Ralf
Medizinische Klinik B, Klinikum Ludwigshafen, Bremserstraße 79, 67063, Ludwigshafen, Deutschland.
Herz. 2025 Sep 11. doi: 10.1007/s00059-025-05338-6.
Patients with an implantable cardioverter defibrillator (ICD) who receive an appropriate ICD shock are known to subsequently have a worse prognosis. Despite the knowledge about the poorer prognosis, in the guidelines there are no clear instructions on how to proceed after the occurrence of an adequate ICD shock. The ToVAMI concept represents a treatment regimen for patients with first appropriate ICD shock after ventricular tachycardia (VT) or ventricular fibrillation (VF) and consists of three steps: 1) To = trigger optimization with the following triggers summarized under the acronym ICD-STEMi (ischemia, compliance, decompensation, stress, technical issue, electrolyte/endocrinological disorder and medication intoxication), 2) VA = ventricular arrhythmia treatment and 3) MI = medicinal and interventional prognostic heart failure treatment. The treatment after the first ICD shock consists not only of ablation or antiarrhythmic treatment but also encompasses a comprehensive suite of diagnostic and therapeutic measures, which require a systematic approach. The systematic application of this regimen can increase the detection rate of trigger factors for VT/VF and essentially contributes to an optimized medicinal and interventional prognostic heart failure treatment. Approximately 10% of patients have no clinical symptoms of worsening heart failure or ischemia during the first ICD shock, despite objective evidence of progressive heart failure or ischemia. In these patients, the first VT/VF shock is the sole warning signal for worsening of the cardiac status. This underscores the need for a systematic diagnostic work-up and treatment after the first ICD shock.
植入式心脏复律除颤器(ICD)患者若接受了恰当的ICD电击治疗,后续预后往往较差。尽管了解到预后较差,但在相关指南中,对于发生恰当的ICD电击后如何处理并无明确指导。ToVAMI概念代表了一种针对室性心动过速(VT)或室颤(VF)后首次接受恰当ICD电击的患者的治疗方案,包括三个步骤:1)To = 通过以下触发因素优化触发,这些触发因素以ICD - STEMi(缺血、顺应性、失代偿、应激、技术问题、电解质/内分泌紊乱和药物中毒)的首字母缩写概括;2)VA = 室性心律失常治疗;3)MI = 药物及介入性预后心力衰竭治疗。首次ICD电击后的治疗不仅包括消融或抗心律失常治疗,还涵盖一系列全面的诊断和治疗措施,这需要系统的方法。系统应用该方案可提高VT/VF触发因素的检出率,并从根本上有助于优化药物及介入性预后心力衰竭治疗。约10%的患者在首次ICD电击时虽无心力衰竭或缺血恶化的临床症状,但存在心力衰竭或缺血进展的客观证据。在这些患者中,首次VT/VF电击是心脏状况恶化的唯一警示信号。这凸显了首次ICD电击后进行系统诊断检查和治疗的必要性。