Johnson Tori, Chan-Sanchez Shirley, Pham Tuan, Gomez Mariangela
Department of Anatomical and Clinical Pathology, University of Texas Medical Branch, Galveston, TX, USA.
SAGE Open Med Case Rep. 2025 Sep 7;13:2050313X251372003. doi: 10.1177/2050313X251372003. eCollection 2025.
Gallium-68 DOTA-Tyr-octreotate positron emission tomography scan is an important radiologic tool for detecting neuroendocrine tumors. It detects neoplasms by capturing the tumor's increased density of somatostatin receptor expression. However, multiple neoplastic and non-neoplastic entities express somatostatin receptors, which can be misleading for proper diagnosis. Herein, we report a case of squamous cell carcinoma in a 64-year-old male with a medical history of 20-pack-years of smoking in which a neuroendocrine tumor was suspected per positive gallium-68 DOTA-Tyr-octreotate imaging. He underwent surgical resection and adjuvant radiation with 6-month post-treatment surveillance positron emission tomography/computed tomography imaging pending.
镓-68 DOTA-酪胺-奥曲肽正电子发射断层扫描是检测神经内分泌肿瘤的重要放射学工具。它通过捕捉肿瘤中生长抑素受体表达密度的增加来检测肿瘤。然而，多种肿瘤性和非肿瘤性实体均表达生长抑素受体，这可能会对准确诊断产生误导。在此，我们报告一例64岁男性鳞状细胞癌病例，该患者有20年20包年的吸烟史，镓-68 DOTA-酪胺-奥曲肽成像呈阳性，怀疑为神经内分泌肿瘤。他接受了手术切除和辅助放疗，治疗后6个月的正电子发射断层扫描/计算机断层扫描成像监测待定。
