Suppr超能文献

在边缘型人格障碍中,分离体验介导童年创伤与言语性幻听之间的关联,但不介导与妄想性思维之间的关联。

Dissociative experiences mediate the association between childhood trauma and verbal hallucinations, but not delusional thoughts, in borderline personality disorder.

作者信息

Schroeder Katrin, Schätzle Anja, Schäfer Ingo, Huber Christian G

机构信息

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Universitäre Psychiatrische Kliniken Basel, University of Basel, Basel, Switzerland.

出版信息

Front Psychiatry. 2025 Aug 26;16:1532234. doi: 10.3389/fpsyt.2025.1532234. eCollection 2025.

Abstract

INTRODUCTION

Auditory verbal hallucinations (AVH), a disturbance of auditory perception, and delusions, a content-related thought disorder, are common in borderline personality disorder (BPD). However, they are not as thoroughly studied and clinically acknowledged as other symptoms. Associations between childhood trauma, dissociative symptoms, and AVH-as well as delusions-have been reported in schizophrenia but remain understudied in BPD.

METHODS

We calculated Pearson's correlations and tested the mediating effects of dissociative symptoms, assessed with the Dissociative Experiences Scale (DES), on the association between childhood trauma, assessed with the Childhood Trauma Questionnaire (CTQ), and both AVH and delusions. A total of 74 BPD patients were examined using the Psychotic Symptoms Rating Scale (PSYRATS) interview. For the mediation analyses, Preacher and Hayes' SPSS bootstrap macro was used to estimate the significance of the mediator.

RESULTS

AVH were reported by 10 patients (13.5%) and delusional thoughts by eight patients (10.8%). In the mediator analyses, dissociative experiences significantly mediated the association between childhood trauma and auditory verbal hallucinations, with an unstandardized regression coefficient between CTQ-Total and DES-Total of = 10.0083; = 0.0008 and between DES-Total and PSYRATS-AVH of = 0.0102; = 0.0009. The relationship between CTQ-Total and the PSYRATS-Delusions Scale was not significantly mediated by DES-Total.

DISCUSSION

The results of the mediation analyses are similar to those shown in schizophrenia, suggesting that the examined symptoms in BPD may underlie similar mechanisms. Further research should examine the benefit of the therapeutic approaches for each of the trauma-associated symptom clusters.

摘要

引言

幻听(AVH)是一种听觉感知障碍,而妄想是一种与内容相关的思维障碍,在边缘型人格障碍(BPD)中很常见。然而,它们并未像其他症状那样得到充分研究和临床认可。童年创伤、分离症状与幻听以及妄想之间的关联在精神分裂症中已有报道,但在BPD中仍未得到充分研究。

方法

我们计算了Pearson相关性,并测试了用分离体验量表(DES)评估的分离症状在童年创伤(用童年创伤问卷(CTQ)评估)与幻听和妄想之间的关联中的中介作用。使用精神病症状评定量表(PSYRATS)访谈对74名BPD患者进行了检查。对于中介分析,使用Preacher和Hayes的SPSS自抽样宏来估计中介的显著性。

结果

10名患者(13.5%)报告有幻听,8名患者(10.8%)报告有妄想性思维。在中介分析中,分离体验显著介导了童年创伤与幻听之间的关联,CTQ总分与DES总分之间的非标准化回归系数为 = 10.0083; = 0.0008,DES总分与PSYRATS-AVH之间的非标准化回归系数为 = 0.0102; = 0.0009。CTQ总分与PSYRATS-妄想量表之间的关系未被DES总分显著介导。

讨论

中介分析的结果与精神分裂症中的结果相似,表明BPD中所研究的症状可能有相似的机制。进一步的研究应考察针对每个与创伤相关的症状群的治疗方法的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0d/12417480/7d7be2f1f400/fpsyt-16-1532234-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验