Oyadomari Sarah, Ranawat Anil, Wang Dean
Department of Orthopaedic Surgery, University of California, Irvine, Irvine, California, U.S.A.
Hospital for Special Surgery, New York, New York, U.S.A.
Arthrosc Tech. 2025 Jul 2;14(8):103721. doi: 10.1016/j.eats.2025.103721. eCollection 2025 Aug.
Autologous bone marrow aspirate (BMA) is increasingly being used in clinical practice to augment the repair and healing of bone, cartilage, and tendon by delivering mesenchymal stem cells (MSCs) and growth factors to the site of injury. Traditional BMA harvest and preparation rely on centrifugation to generate a BMA concentrate with a higher concentration of MSCs than the original aspirate. However, this traditional technique may be inefficient and time-consuming, and it could sacrifice sterility. In this technique, we describe a centrifuge-free BMA harvest system (Marrow Cellution; Cervos Medical) that avoids peripheral blood dilution during aspiration, thereby potentially achieving a higher yield of MSCs and growth factors within the BMA without the need for centrifugation.
自体骨髓抽吸物（BMA）在临床实践中越来越多地被用于通过将间充质干细胞（MSC）和生长因子输送到损伤部位来增强骨、软骨和肌腱的修复与愈合。传统的BMA采集和制备依靠离心来生成比原始抽吸物中MSC浓度更高的BMA浓缩物。然而，这种传统技术可能效率低下且耗时，还可能牺牲无菌性。在本技术中，我们描述了一种无需离心的BMA采集系统（Marrow Cellution；Cervos Medical），该系统在抽吸过程中避免外周血稀释，从而有可能在无需离心的情况下在BMA中获得更高产量的MSC和生长因子。
