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恶性心包食管瘘导致的念珠菌性心包炎和心包填塞

Candida pericarditis and tamponade from a malignant pericardio-oesophageal fistula.

作者信息

Wills Nicola K, Arnab Priyadarshini, Oompie Ferdinand, Papavarnavas Nectarios S

机构信息

Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Division of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

出版信息

S Afr J Infect Dis. 2025 Aug 31;40(1):741. doi: 10.4102/sajid.v40i1.741. eCollection 2025.

DOI:10.4102/sajid.v40i1.741
PMID:40936587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12421550/
Abstract

UNLABELLED

We describe the case of a middle-aged man and long-term smoker, presenting in cardiac tamponade with paroxysmal atrial flutter, with translocation of into the pericardial space as a result of an erosive malignant oesophago-pericardial fistula.

CONTRIBUTION

The isolation of species from the pericardial space is a rare manifestation of invasive candida infection, carrying a high mortality rate, and requires interrogation for possible underlying immune aberrations or mechanical portals of entry.

摘要

未标注

我们描述了一名中年男性且长期吸烟患者的病例,该患者因侵蚀性恶性食管心包瘘导致[此处原文缺失具体物质]进入心包腔,出现心脏压塞并伴有阵发性心房扑动。

贡献

从心包腔分离出[此处原文缺失具体物种]是侵袭性念珠菌感染的罕见表现,死亡率很高,需要探究可能存在的潜在免疫异常或机械性入口。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faf/12421550/b93af09b8386/SAJID-40-741-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faf/12421550/e643c5ad5564/SAJID-40-741-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faf/12421550/b93af09b8386/SAJID-40-741-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faf/12421550/e643c5ad5564/SAJID-40-741-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faf/12421550/b93af09b8386/SAJID-40-741-g002.jpg

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本文引用的文献

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Lancet Infect Dis. 2025 May;25(5):e280-e293. doi: 10.1016/S1473-3099(24)00749-7. Epub 2025 Feb 13.
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Case report: cardiac tamponade secondary to candida pericarditis.病例报告:念珠菌性心包炎继发心脏压塞
J Surg Case Rep. 2024 Mar 15;2024(3):rjae150. doi: 10.1093/jscr/rjae150. eCollection 2024 Mar.
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A fatal Candida albicans pericarditis presenting with cardiac tamponade after COVID-19 infection and cardiothoracic surgery.
COVID-19 感染及心胸手术后致命性白念珠菌性心包炎并发心脏压塞
J Clin Lab Anal. 2023 Oct;37(19-20):e24968. doi: 10.1002/jcla.24968. Epub 2023 Oct 6.
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Diagnosis and Treatment of Invasive Candidiasis.侵袭性念珠菌病的诊断与治疗
Antibiotics (Basel). 2022 May 26;11(6):718. doi: 10.3390/antibiotics11060718.
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Pericardial Effusion Provoking Atrial Fibrillation After Cardiac Surgery: JACC Review Topic of the Week.心脏手术后心包积液引发心房颤动:JACC 每周综述专题。
J Am Coll Cardiol. 2022 Jun 28;79(25):2529-2539. doi: 10.1016/j.jacc.2022.04.029.
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Invasive candidiasis in critical care: challenges and future directions.重症监护中的侵袭性念珠菌病:挑战与未来方向。
Intensive Care Med. 2020 Nov;46(11):2001-2014. doi: 10.1007/s00134-020-06240-x. Epub 2020 Sep 29.
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Chronic disseminated candidiasis manifesting as hepatosplenic abscesses among patients with hematological malignancies.慢性播散性念珠菌病表现为血液恶性肿瘤患者的肝脾脓肿。
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A case report of purulent pericarditis caused by Candida albicans: Delayed complication forty-years after esophageal surgery.
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Invasive Candidiasis.侵袭性念珠菌病
N Engl J Med. 2015 Oct 8;373(15):1445-56. doi: 10.1056/NEJMra1315399.
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Two unlike cousins: Candida albicans and C. glabrata infection strategies.两种不同的表亲:白念珠菌和光滑念珠菌的感染策略。
Cell Microbiol. 2013 May;15(5):701-8. doi: 10.1111/cmi.12091. Epub 2013 Jan 14.