Oliveira Isabele de Matos, da Rosa Desirée Santos, da Silva Laryssa Reginaldo Ribeiro, de Souza Yasmin Santos Kaulich, Ribeiro Mateus Siarense, Castro Gustavo Nunes de Santana
Universidade Iguaçu, c I, Nova Iguaçu, RJ, Brazil.
Braz J Vet Med. 2025 Sep 4;47:e000925. doi: 10.29374/2527-2179.bjvm000925. eCollection 2025.
Breast tumors are common in female dogs, and in most cases, unilateral mastectomy is the surgical technique. This procedure poses a considerable risk for the development of post-surgical chronic pain. Therefore, the animal must have a good analgesic plan during the intraoperative period. This study aimed to evaluate the analgesic potential of the serratus plane (SP) block when combined with the transversus abdominis plane (TAP) block during the intraoperative and postoperative periods in female dogs undergoing mastectomy. Eighteen female dogs, aged 5-15 years and weighing 4-77 lbs, with mammary tumors staged I-III, were referred for total unilateral mastectomy. These dogs were pre-medicated with 0.03 mg/kg intramuscular acepromazine, an anesthetic was induced with propofol, and maintained with isoflurane. The dogs were divided into two groups: in 10 dogs, TAP blocks were performed with a volume of 0.4 mL/kg, combined with SP blocks with a volume of 0.4 mL/kg of 0.25% bupivacaine intraoperatively, before starting surgery, and in another eight dogs, tumescent anesthesia was performed with a cold solution containing lactated Ringer's, 2% lidocaine without vasoconstrictor, and adrenaline in 15 mL/kg intraoperatively. During data collection, analysis, interpretation of results, and subject follow-up, no group exhibited a response to nociceptive stimuli during the intraoperative period. In the postoperative period, only one dog from group 1 presented with a score greater than 5, and a slight delay in anesthetic recovery was observed in dogs from group 2. The evaluation of parameters during and after surgery, combined with the low need for analgesics in most female dogs, indicated that the combination of TAP and SP blocks was effective for analgesic control. In conclusion, this combination is an alternative to promote analgesia and favor recovery in female dogs undergoing mastectomy.
乳腺肿瘤在雌性犬中很常见，在大多数情况下，单侧乳房切除术是手术方式。该手术对术后慢性疼痛的发生构成相当大的风险。因此，动物在手术期间必须有良好的镇痛方案。本研究旨在评估在接受乳房切除术的雌性犬的术中和术后期间，锯肌平面（SP）阻滞与腹横肌平面（TAP）阻滞联合使用时的镇痛潜力。18只年龄在5至15岁、体重4至77磅、乳腺肿瘤分期为I - III期的雌性犬被转诊进行单侧乳房全切术。这些犬术前肌肉注射0.03 mg/kg乙酰丙嗪进行预处理，用丙泊酚诱导麻醉，并用异氟醚维持麻醉。犬被分为两组：10只犬在手术开始前术中进行TAP阻滞，剂量为0.4 mL/kg，同时联合SP阻滞，剂量为0.4 mL/kg的0.25%布比卡因；另外8只犬在术中用含乳酸林格氏液、2%无血管收缩剂利多卡因和肾上腺素的冷溶液按15 mL/kg进行肿胀麻醉。在数据收集、分析、结果解释和受试者随访期间，术中没有一组表现出对伤害性刺激的反应。在术后期间，只有第1组的1只犬评分大于5，并且观察到第2组的犬麻醉恢复略有延迟。手术期间和术后对参数的评估，以及大多数雌性犬对镇痛药的低需求，表明TAP和SP阻滞联合使用对镇痛控制有效。总之，这种联合是促进接受乳房切除术的雌性犬镇痛和利于恢复的一种替代方法。
