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右股骨远端内侧髁软骨母细胞瘤:一例报告

Chondroblastoma of the Right Distal Femur Medial Condyle: A Case Report.

作者信息

Naaharaaj Sabare, Tavfiq Mohammed, Harshavardhan J K Giriraj, Vijayan Balaji

机构信息

Department of Orthopedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

出版信息

J Orthop Case Rep. 2025 Sep;15(9):213-218. doi: 10.13107/jocr.2025.v15.i09.6074.

DOI:10.13107/jocr.2025.v15.i09.6074
PMID:40936816
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12422696/
Abstract

INTRODUCTION

Chondroblastoma is a rare, benign but locally aggressive bone tumor typically affecting adolescents and young adults. It commonly arises in the epiphyseal region of long bones, particularly the distal femur. Despite its benign nature, it can cause significant joint dysfunction, pain, and disability. Early diagnosis is critical for preserving joint function and preventing recurrence.

CASE REPORT

A 15-year-old female presented with progressive right knee pain of 6 months' duration, worsened by weight-bearing and minimally relieved by analgesics. Clinical examination revealed tenderness and immobile swelling in the region of the medial femoral condyle. Imaging showed characteristic "chicken-wire" calcification, and computed tomography-guided biopsy confirmed chondroblastoma. The patient underwent extended curettage, iliac crest bone grafting, and the use of synthetic bone substitutes. Post-operative rehabilitation showed a good recovery in range of motion and limb function, with no recurrence at follow-up.

CONCLUSION

Early diagnosis and appropriate surgical management, including extended curettage and bone grafting, are essential to prevent recurrence and restore joint function in distal femur chondroblastoma. Functional outcomes are generally favorable with timely and targeted treatment.

摘要

引言

软骨母细胞瘤是一种罕见的、良性但具有局部侵袭性的骨肿瘤,通常影响青少年和年轻成年人。它常见于长骨的骨骺区域,尤其是股骨远端。尽管其本质为良性,但可导致严重的关节功能障碍、疼痛和残疾。早期诊断对于保留关节功能和预防复发至关重要。

病例报告

一名15岁女性出现持续6个月的进行性右膝疼痛,负重时加重,使用镇痛药后稍有缓解。临床检查发现股骨内侧髁区域有压痛和固定性肿胀。影像学检查显示特征性的“筛孔状”钙化,计算机断层扫描引导下的活检证实为软骨母细胞瘤。患者接受了扩大刮除术、髂骨植骨及使用人工骨替代物。术后康复显示关节活动范围和肢体功能恢复良好,随访期间无复发。

结论

早期诊断和适当的手术治疗,包括扩大刮除术和植骨,对于预防股骨远端软骨母细胞瘤的复发和恢复关节功能至关重要。及时且有针对性的治疗通常可取得良好的功能预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/675234e35ddc/JOCR-15-213-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/c27c4481e158/JOCR-15-213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/fde8c11341fd/JOCR-15-213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/b973fe6a4477/JOCR-15-213-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/67842ebd8140/JOCR-15-213-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/e705210e59e4/JOCR-15-213-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/675234e35ddc/JOCR-15-213-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/c27c4481e158/JOCR-15-213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/fde8c11341fd/JOCR-15-213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae0b/12422696/b973fe6a4477/JOCR-15-213-g003.jpg
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