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一例罕见的晚期嫌色性肾细胞癌转移且病程缓慢的病例。

A rare case of late chromophobe RCC metastasis with indolent course.

作者信息

Anastasiou Periklis, Douroumis Konstantinos, Panagopoulos Panagiotis, Katsikatsos Panagiotis, Kalfountzos Christos, Davakis Spyridon, Anastasiou Ioannis

机构信息

Faculty of Medicine, School of Health Sciences, University of Ioannina, Bizani, Ioannina, 45500, Greece.

First Department of Urology, National and Kapodistrian University of Athens, Medical School, Agiou Thoma 17, Goudi, Athens, 11527, Greece.

出版信息

Urol Case Rep. 2025 Aug 25;63:103180. doi: 10.1016/j.eucr.2025.103180. eCollection 2025 Nov.

Abstract

Renal cell carcinoma (RCC) is the predominant solid lesion of the kidney. Among the various subtypes of RCC, chromophobe RCC (chRCC) is relatively rare, and it is characterized by an indolent clinical course and a favourable prognosis. We present a rare case of a 40-year-old patient who developed a retroperitoneal metastasis four years after undergoing radical nephrectomy for chRCC. The patient was under surveillance for another six years before surgical excision of the recurrence was performed. This case underscores the potential for late recurrence in chRCC and highlights the importance of long-term surveillance, even in patients with an initially favourable prognosis.

摘要

肾细胞癌(RCC)是肾脏的主要实体病变。在RCC的各种亚型中,嫌色肾细胞癌(chRCC)相对少见,其临床病程进展缓慢,预后良好。我们报告了一例罕见病例,一名40岁患者在接受chRCC根治性肾切除术后四年出现腹膜后转移。在对该复发灶进行手术切除前,患者又接受了六年的监测。该病例强调了chRCC存在晚期复发的可能性,并突出了长期监测的重要性,即使是对初始预后良好的患者也是如此。

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