Undhad Hiral, Joshi Pooja, Patil Nidhi, Uppal Neha, Bedi Simranjeet
Internal Medicine, Jiangsu University School of Medicine, Zhenjiang, CHN.
Medicine, Kanti Devi Medical College, Hospital and Research Center, Mathura, IND.
Cureus. 2025 Sep 9;17(9):e91920. doi: 10.7759/cureus.91920. eCollection 2025 Sep.
Lymphoid leukemia is a major cause of death, and its link with septicemia is progressively studied. It is crucial to understand that the relationship is important for identifying high-risk populations and designing targeted public health interventions.
This study aims to evaluate mortality trends in lymphoid leukemia with septicemia as a contributing cause of death, using the CDC Multiple Causes of Death (MCD) database.
A study retrospectively examined data from the CDC MCD database to determine trends in deaths among individuals 25 years and older in the US from 1999 through 2020. They examined deaths with lymphoid leukemia as the underlying cause of death and septicemia as a contributing cause. The data were categorized by sex, race, geographic region, and location of death. Age-adjusted mortality rate (AAMR) and annual percentage change (APC) were calculated.
From 1999 to 2020, 17,265 adults over 25 died with lymphoid leukemia and septicemia. Most deaths occurred in metropolitan areas (N = 14,267, 82.6%). Males (N = 10,825, 62.7%) and White individuals (N = 14,953, 86.6%) had the highest mortality. The crude death rate was 3.9 per million population.
This study highlights significant mortality trends increasing in lymphoid leukemia with septicemia with disparities by gender and race. Findings underscore the need for targeted prevention strategies and improved healthcare access.
淋巴样白血病是主要死因之一，其与败血症的关联正逐步得到研究。了解这种关系对于识别高危人群和设计有针对性的公共卫生干预措施至关重要。
本研究旨在利用美国疾病控制与预防中心（CDC）的多重死因（MCD）数据库，评估以败血症作为促成死因的淋巴样白血病的死亡率趋势。
一项研究回顾性分析了CDC MCD数据库中的数据，以确定1999年至2020年美国25岁及以上人群的死亡趋势。他们研究了以淋巴样白血病为根本死因且败血症为促成死因的死亡情况。数据按性别、种族、地理区域和死亡地点进行分类。计算了年龄调整死亡率（AAMR）和年度百分比变化（APC）。
1999年至2020年，17265名25岁以上成年人死于淋巴样白血病和败血症。大多数死亡发生在大都市地区（n = 14267，82.6%）。男性（n = 10825，62.7%）和白人个体（n = 14953，86.6%）的死亡率最高。粗死亡率为每百万人口3.9人。
本研究突出了以败血症为促成死因的淋巴样白血病死亡率显著上升的趋势，且存在性别和种族差异。研究结果强调了制定针对性预防策略和改善医疗服务可及性的必要性。
