Han Han, Ye Shuling, Xie Mengjuan, Yu Xin, Wu Renrong, Liu Dengtang, Hu Shaohua, Xu Yong, Liu Huanzhong, Wang Xijin, Zhu Gang, Wang Huaning, Zou Shaohong, Li Tao, Guo Wanjun, Xu Xiufeng, Cheng Yuqi, Li Yi, Yang Juan, Peng Min, Shi Chuan
Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing 100096, China.
Peking University Institute of Mental Health (Sixth Hospital), Beijing 100191, China.
Schizophr Res Cogn. 2025 Aug 31;42:100386. doi: 10.1016/j.scog.2025.100386. eCollection 2025 Dec.
To complete the preparation of the electronic version of C-BCT, verifying the criterion validity of the electronic version of C-BCT.
747 healthy subjects and 139 schizophrenics completed the electronic version of C-BCT and MCCB. To measure psychotic symptoms and severity, patients with schizophrenia completed the PANSS scale. Mean, standard deviation, percentage, etc. were used to describe demographic variables. One-way analysis of variance and independent sample test were used to compare differences between groups. MCCB as a calibration tool, criterion validity was examined using Pearson product moment correlations.
In the equivalence analysis of the healthy group, all tests have good calibration validity ( < 0.01). SC and TMT-A showed moderate correlation (r- value ranged from 0.572 to 0.651, < 0.01), DS showed a weak correlation( = 0.373, < 0.01), CPT showed a weak correlation (r- value ranged from 0.219 to 0.444, < 0.01), the comprehensive scores of the two sets of cognitive tools showed a strong correlation ( = 0.739, p < 0.01). In the equivalence analysis of the patient group, TMT-A and SC showed strong correlation (r- value ranged from 0.754 to 0.803, p < 0.01), DS showed a weak correlation ( = 0.381, < 0.01), the cognitive tools comprehensive score was significantly strong correlation ( = 0.755, p < 0.01), there was no correlation between CPT( > 0.05). In the healthy group, there was a correlation between the scores of each subtest of the electronic version of C-BCT and the comprehensive scores of the two cognition tools, (r- value ranged from 0.261 to 0.824, < 0.01). In the patient group, there was a correlation between the scores of each subtest and the comprehensive scores of the two tools,(r- value ranged from 0.266 to 0.778, p < 0.01).
The electronic version of C-BCT has been compiled. The electronic version of the C-BCT performs well in overall calibration validity and could be used to assess the cognitive function of schizophrenia.
完成中文版计算机化神经认知成套测验(C-BCT)电子版的编制,并验证其效度。
747名健康受试者和139名精神分裂症患者完成了C-BCT电子版和成套神经心理状态测验(MCCB)。为测量精神症状及严重程度,精神分裂症患者完成阳性和阴性症状量表(PANSS)。采用均值、标准差、百分比等描述人口统计学变量。采用单因素方差分析和独立样本检验比较组间差异。以MCCB作为校准工具,采用Pearson积差相关分析检验效度。
在健康组的等效性分析中,所有测验均具有良好的校准效度(<0.01)。符号编码(SC)和连线测验A(TMT-A)呈中度相关(r值范围为0.572至0.651,<0.01),数字广度(DS)呈弱相关(=0.373,<0.01),连续性能测验(CPT)呈弱相关(r值范围为0.219至0.444,<0.01),两组认知工具的综合得分呈强相关(=0.739,p<0.01)。在患者组的等效性分析中,TMT-A和SC呈强相关(r值范围为0.754至0.803,p<0.01),DS呈弱相关(=0.381,<0.01),认知工具综合得分呈显著强相关(=0.755,p<0.01),CPT之间无相关性(>0.05)。在健康组中,C-BCT电子版各子测验得分与两种认知工具综合得分之间存在相关性(r值范围为0.261至0.824,<0.01)。在患者组中,各子测验得分与两种工具综合得分之间存在相关性(r值范围为0.266至0.778,p<0.01)。
已完成C-BCT电子版的编制。C-BCT电子版在整体校准效度方面表现良好,可用于评估精神分裂症的认知功能。