西班牙首发精神分裂症患者的 MCCB 认知特征。
MCCB cognitive profile in Spanish first episode schizophrenia patients.
机构信息
Department of Psychiatry, Instituto de Investigación Sanitaria Hospital, 12 de Octubre (imas12), Madrid, Spain; CIBERSAM (Biomedical Research Networking Centre in Mental Health), Spain; Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain.
CIBERSAM (Biomedical Research Networking Centre in Mental Health), Spain; Department of Psychiatry, Hospital Virgen de La Luz, Cuenca, Spain.
出版信息
Schizophr Res. 2019 Sep;211:88-92. doi: 10.1016/j.schres.2019.07.011. Epub 2019 Jul 22.
The objective of the study was to examine the cognitive profile of Spanish patients with a first episode of schizophrenia (FESz) and to compare that to the profile of patients with a chronic schizophrenia (CSz) and non-psychiatric (NP) control subjects. The study included 106 FESz, 293 CSz, and 210 NP, assessed with the Spanish version of the MATRICS Consensus Cognitive Battery (MCCB). The MCCB cognitive profile in a Spanish sample of FESz was similar to the cognitive profile of CSz with some discrepancies in select domains. The scores of both patient samples were about 1-2 SD below the scores of non-psychiatric control subjects.
本研究旨在探讨西班牙首发精神分裂症（FESz）患者的认知特征，并将其与慢性精神分裂症（CSz）患者和非精神病（NP）对照组的特征进行比较。研究纳入了 106 例 FESz、293 例 CSz 和 210 例 NP 患者，采用 MATRICS 共识认知电池（MCCB）的西班牙语版本进行评估。西班牙首发精神分裂症患者样本的 MCCB 认知特征与慢性精神分裂症患者的认知特征相似，但在某些特定领域存在差异。两个患者样本的得分均比非精神病对照组低约 1-2 个标准差。
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