• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

KLF2 Promotes Neutrophil Apoptosis in Mice with Myocardial ischemia-reperfusion Injury by Upregulating Notch1.

作者信息

Nie Furu, Deng Xu

机构信息

Cardiovascular Department III, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha, 410006, Hunan, China.

Department of Cardiology, the Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.

出版信息

Cell Biochem Biophys. 2025 Sep 12. doi: 10.1007/s12013-025-01889-x.

DOI:10.1007/s12013-025-01889-x
PMID:40938482
Abstract
摘要

相似文献

1
KLF2 Promotes Neutrophil Apoptosis in Mice with Myocardial ischemia-reperfusion Injury by Upregulating Notch1.KLF2通过上调Notch1促进心肌缺血再灌注损伤小鼠中性粒细胞凋亡。
Cell Biochem Biophys. 2025 Sep 12. doi: 10.1007/s12013-025-01889-x.
2
ZLY032 mediated activation of Notch1/Hes1 signaling inhibits cardiomyocyte ferroptosis to protect against myocardial Ischemia-Reperfusion injury in mice.ZLY032介导的Notch1/Hes1信号激活抑制心肌细胞铁死亡，以保护小鼠免受心肌缺血再灌注损伤。
Biochem Pharmacol. 2025 Sep;239:117039. doi: 10.1016/j.bcp.2025.117039. Epub 2025 Jun 9.
3
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis.淋巴结外泌体递送通过调节PTEN-PI3K/Akt信号通路介导的心肌细胞凋亡减轻心肌缺血-再灌注损伤。
Int J Nanomedicine. 2025 Apr 17;20:4967-4981. doi: 10.2147/IJN.S512135. eCollection 2025.
4
CD11b Blockade Ameliorates Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil and Monocyte Infiltration.CD11b阻断通过减少中性粒细胞和单核细胞浸润改善心肌缺血/再灌注损伤。
J Am Heart Assoc. 2025 Jul;14(13):e038142. doi: 10.1161/JAHA.124.038142. Epub 2025 Jun 27.
5
[LncRNA-UCA1-microRNA-143-Notch1 regulates autophagy in myocardial ischemia reperfusion injury induced by cardiopulmonary bypass].[长链非编码RNA-UCA1-微小RNA-143-Notch1调控体外循环诱导的心肌缺血再灌注损伤中的自噬]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2025 Jun;37(6):576-582. doi: 10.3760/cma.j.cn121430-20240329-00298.
6
[Electroacupuncture promotes angiogenesis in MIRI rats by modulating the AMPK/KLF2 signaling pathway].[电针通过调节AMPK/KLF2信号通路促进心肌缺血再灌注损伤大鼠血管生成]
Zhen Ci Yan Jiu. 2024;49(9):902-908. doi: 10.13702/j.1000-0607.20230141.
7
Extracellular vesicles derived from Krüppel-Like Factor 2-overexpressing endothelial cells attenuate myocardial ischemia-reperfusion injury by preventing Ly6C monocyte recruitment.Krüppel 样因子 2 过表达内皮细胞来源的细胞外囊泡通过防止 Ly6C 单核细胞募集来减轻心肌缺血再灌注损伤。
Theranostics. 2020 Sep 18;10(25):11562-11579. doi: 10.7150/thno.45459. eCollection 2020.
8
B cell subsets contribute to myocardial protection by inducing neutrophil apoptosis after ischemia and reperfusion.B 细胞亚群通过在缺血再灌注后诱导中性粒细胞凋亡来发挥心肌保护作用。
JCI Insight. 2024 Feb 22;9(4):e167201. doi: 10.1172/jci.insight.167201.
9
Suppression of nF-κB by ro 106-9920 alleviates ischemia/reperfusion-induced renal dysfunction and inflammation via modulation of neutrophil extracellular trap formation in acute kidney injury mice.RO 106-9920对核因子κB的抑制作用通过调节急性肾损伤小鼠中性粒细胞胞外诱捕网的形成减轻缺血/再灌注诱导的肾功能障碍和炎症。
Ren Fail. 2025 Dec;47(1):2545983. doi: 10.1080/0886022X.2025.2545983. Epub 2025 Aug 12.
10
TNF-α inhibitor protects against myocardial ischemia/reperfusion injury via Notch1-mediated suppression of oxidative/nitrative stress.肿瘤坏死因子-α抑制剂通过Notch1介导的氧化/硝化应激抑制作用来预防心肌缺血/再灌注损伤。
Free Radic Biol Med. 2015 May;82:114-21. doi: 10.1016/j.freeradbiomed.2015.02.002. Epub 2015 Feb 11.

本文引用的文献

1
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus.KLF2控制中性粒细胞的凋亡，并与系统性红斑狼疮的疾病活动相关。
Arthritis Res Ther. 2024 Dec 19;26(1):222. doi: 10.1186/s13075-024-03461-z.
2
Myocardial ischemia-reperfusion injury: The balance mechanism between mitophagy and NLRP3 inflammasome.心肌缺血再灌注损伤：自噬与 NLRP3 炎性小体之间的平衡机制。
Life Sci. 2024 Oct 15;355:122998. doi: 10.1016/j.lfs.2024.122998. Epub 2024 Aug 20.
3
"Find Me" and "Eat Me" signals: tools to drive phagocytic processes for modulating antitumor immunity.
“找我”和“吃我”信号：用于调节抗肿瘤免疫的吞噬过程的工具。
Cancer Commun (Lond). 2024 Jul;44(7):791-832. doi: 10.1002/cac2.12579. Epub 2024 Jun 23.
4
WTAP-mediated mA modification of lncRNA Snhg1 improves myocardial ischemia-reperfusion injury via miR-361-5p/OPA1-dependent mitochondrial fusion.WTAP 通过介导 lncRNA Snhg1 的 mA 修饰作用改善心肌缺血再灌注损伤，其作用机制是通过 miR-361-5p/OPA1 依赖性线粒体融合。
J Transl Med. 2024 May 25;22(1):499. doi: 10.1186/s12967-024-05330-4.
5
MSC-Derived Exosomes Mitigate Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil Infiltration and the Formation of Neutrophil Extracellular Traps.MSC 来源的外泌体通过减少中性粒细胞浸润和中性粒细胞细胞外陷阱的形成来减轻心肌缺血/再灌注损伤。
Int J Nanomedicine. 2024 Mar 5;19:2071-2090. doi: 10.2147/IJN.S436925. eCollection 2024.
6
B cell subsets contribute to myocardial protection by inducing neutrophil apoptosis after ischemia and reperfusion.B 细胞亚群通过在缺血再灌注后诱导中性粒细胞凋亡来发挥心肌保护作用。
JCI Insight. 2024 Feb 22;9(4):e167201. doi: 10.1172/jci.insight.167201.
7
Dying to Defend: Neutrophil Death Pathways and their Implications in Immunity.《垂死防御：中性粒细胞死亡途径及其在免疫中的意义》。
Adv Sci (Weinh). 2024 Feb;11(8):e2306457. doi: 10.1002/advs.202306457. Epub 2023 Dec 3.
8
Inflammation in Myocardial Ischemia/Reperfusion Injury: Underlying Mechanisms and Therapeutic Potential.心肌缺血/再灌注损伤中的炎症：潜在机制与治疗潜力
Antioxidants (Basel). 2023 Oct 31;12(11):1944. doi: 10.3390/antiox12111944.
9
FGF2 Alleviates Microvascular Ischemia-Reperfusion Injury by KLF2-mediated Ferroptosis Inhibition and Antioxidant Responses.FGF2 通过 KLF2 介导的铁死亡抑制和抗氧化反应减轻微血管缺血再灌注损伤。
Int J Biol Sci. 2023 Aug 21;19(13):4340-4359. doi: 10.7150/ijbs.85692. eCollection 2023.
10
Kindlin-2 controls angiogenesis through modulating Notch1 signaling.Kindlin-2 通过调节 Notch1 信号通路控制血管生成。
Cell Mol Life Sci. 2023 Jul 22;80(8):223. doi: 10.1007/s00018-023-04866-w.