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曼苏拉大学输血中心血液成分的内部质量评估

Internal quality assessment of blood components at Mansoura university blood transfusion center.

作者信息

Shahin Doaa, Tawfeek Amira M, Khaled Omnia, Mortada Metwaly I

机构信息

Haematology Unit, Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, 35111, Egypt.

Clinical Pathology Department, Faculty of Medicine, Damietta University, Damietta, Egypt.

出版信息

Sci Rep. 2025 Sep 12;15(1):32501. doi: 10.1038/s41598-025-17334-1.

Abstract

In modern blood banking, quality control of blood products ensures the timely availability of a blood component of high-quality yield with maximum efficacy and minimal risk to potential recipients. A prospective cross-sectional study was carried out at Mansoura University Hospital Blood Bank (MUHBB) aiming to assess the internal quality control (IQC) of 300 units of each blood components, red blood cell concentrates (RBCs), fresh frozen plasma (FFP), and platelet concentrates (PCs), and to explore their compliance with The Egyptian National Blood Transfusion Services (NBTS ),The American Association of Blood Banks (AABB), and Council of Europe (CE) standard criteria. IQC of different blood products was accepted if > 90% of units were fulfilled the standard requirements. The results of our study show that the total compliance of RBCs was 93.3% according to NBTS and CE standards and 96% as regards AABB standards. The total compliance of FFP was 94.0% according to NBTS and CE standards and 96.0% as regards AABB standards. While the total compliance of PCs was 96.0% according to NBTS and AABB standards and 93.3% as regards CE standards. Continuous improvement is recommended to decrease the percentage of noncompliance in the QC parameters included in our study and to uplift the blood transfusion practices.

摘要

在现代血液库中,血液制品的质量控制可确保及时提供高质量产出的血液成分,使其对潜在受血者具有最大功效且风险最小。在曼苏拉大学医院血库(MUHBB)开展了一项前瞻性横断面研究,旨在评估每种血液成分(红细胞浓缩液(RBCs)、新鲜冰冻血浆(FFP)和血小板浓缩液(PCs))300单位的内部质量控制(IQC),并探讨它们是否符合埃及国家输血服务局(NBTS)、美国血库协会(AABB)和欧洲理事会(CE)的标准准则。如果超过90%的单位符合标准要求,则不同血液制品的IQC被视为合格。我们的研究结果表明,根据NBTS和CE标准,RBCs的总体合格率为93.3%,而根据AABB标准则为96%。根据NBTS和CE标准,FFP的总体合格率为94.0%,而根据AABB标准则为96.0%。而根据NBTS和AABB标准,PCs的总体合格率为96.0%,根据CE标准则为93.3%。建议持续改进,以降低我们研究中所包含的质量控制参数的不合格率,并提升输血实践水平。

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