Di Duca Fabiana, Montuori Paolo, De Rosa Elvira, Russo Immacolata, Palladino Raffaele, Scippa Stefano, Dadà Giuseppe, Triassi Maria, Díez Sergi
Department of Public Health, University "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Department of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, Italy.
Foods. 2025 Aug 26;14(17):2968. doi: 10.3390/foods14172968.
The growing use of plastics in food packaging has raised concerns about chemical migration into consumables, posing potential health risks. Ensuring the safety of packaging materials is a critical public health priority. This study aimed to validate an analytical method for qualitative and quantitative determination of BPs in bottled water and evaluate their presence in PET and rPET matrices. The method was validated through recovery tests for eight BPs (Bisphenol A, Bisphenol S, Bisphenol F, Bisphenol AF, Bisphenol AP, Bisphenol B, Bisphenol Z, and Bisphenol P). Linearity (R ≥ 0.990) and high recovery rates proved the method's stability, reliability, and accuracy. For bottled water, LODs ranged 0.030-0.075 µg/L and LOQs 0.10-0.25 µg/L; for PET/rPET, LODs were 0.00030-0.00075 mg/kg and LOQs 0.0010-0.0025 mg/kg. Mean recoveries in bottled water were in the range 89-109%, in PET from 94% to 117%, and in rPET from 106% to 118%. The results showed that BPA was quantifiable in all matrices, while other BPs remained below the limit of quantification. The validated method provides a robust tool for assessing bisphenol contamination and supports ongoing efforts to enhance food safety and inform regulatory frameworks for sustainable PET recycling.
食品包装中塑料使用的日益增加引发了人们对化学物质迁移到消费品中的担忧，这带来了潜在的健康风险。确保包装材料的安全是公共卫生的一项关键优先事项。本研究旨在验证一种用于定性和定量测定瓶装水中双酚类物质（BPs）的分析方法，并评估它们在聚对苯二甲酸乙二酯（PET）和回收聚对苯二甲酸乙二酯（rPET）基质中的存在情况。该方法通过对八种双酚类物质（双酚A、双酚S、双酚F、双酚AF、双酚AP、双酚B、双酚Z和双酚P）的回收率测试进行了验证。线性关系（R≥0.990）和高回收率证明了该方法的稳定性、可靠性和准确性。对于瓶装水，检测限（LODs）范围为0.030 - 0.075μg/L，定量限（LOQs）为0.10 - 0.25μg/L；对于PET/rPET，检测限为0.00030 - 0.00075mg/kg，定量限为0.0010 - 0.0025mg/kg。瓶装水中的平均回收率在89% - 109%之间，PET中的回收率为94%至117%，rPET中的回收率为106%至118%。结果表明，双酚A在所有基质中均可定量，而其他双酚类物质仍低于定量限。经过验证的方法为评估双酚污染提供了一个强大的工具，并支持正在进行的加强食品安全的努力，为可持续PET回收的监管框架提供信息。
