Halla J T, Hardin J G, Linn J E
Arthritis Rheum. 1977 Jul-Aug;20(6):1188-91. doi: 10.1002/art.1780200605.
During gold sodium thiomalate (GST) therapy, 15% of 100 unselected patients described recurring postinjection reactions (PIRs), consisting of transient stiffness, arthralgias, myalgias, and constitutional symptoms. Six patients with more severe reactions requested discontinuation of chrysotherapy and for these, gold thioglucose (GTG) substitution abolished or amelioriated the reactions. The major significance of the PIR is that it may be a frequent cause of unwarranted premature abandonment of chrysotherapy.
在硫代苹果酸钠金（GST）治疗期间，100名未经挑选的患者中有15%出现注射后反应复发（PIR），包括短暂性僵硬、关节痛、肌痛和全身症状。6名反应较严重的患者要求停止金疗法，对于这些患者，改用硫代葡萄糖金（GTG）后反应消失或减轻。PIR的主要意义在于，它可能是导致无端过早放弃金疗法的常见原因。
