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皮肤病理学中数字病理学与人工智能的当前趋势及未来方向:基于科学计量学的综述

Current Trends and Future Directions of Digital Pathology and Artificial Intelligence in Dermatopathology: A Scientometric-Based Review.

作者信息

Cocuz Iuliu Gabriel, Niculescu Raluca, Popelea Maria-Cătălina, Cocuz Maria Elena, Sabău Adrian-Horațiu, Tinca Andreea-Cătălina, Cozac-Szoke Andreea Raluca, Chiorean Diana Maria, Budin Corina Eugenia, Cotoi Ovidiu Simion

机构信息

Pathophysiology Department, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, 540142 Targu Mures, Romania.

Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania.

出版信息

Diagnostics (Basel). 2025 Aug 29;15(17):2196. doi: 10.3390/diagnostics15172196.

Abstract

Digital Pathology (DP) and Artificial Intelligence (AI) have strongly developed in recent years, especially in pathology, with a high interest in dermatopathology. Accelerated by the COVID-19 pandemic, DP and AI are now integrated in pathology, research and education, bringing value to histopathological diagnoses, telepathology and personalized medicine. This narrative review presents a comprehensive literature review by defining three research directions, using scientometric analysis, of the current state of DP and AI in pathology and dermatopathology. The research was conducted through the Pubmed and Web of Science databases, within the research period of January 2019-July 2025: a two-phase methodology. Four independent pathologists selected the articles in accordance with the inclusion and exclusion criteria, and the synthesis of the articles was based on three research directions. The research shows that CNN (Convolutional Neural Network), AI powered diagnostic platforms and telepathology strongly contribute to increasing the speed and accuracy of diagnostics, especially on cutaneous malignant skin tumors. There are still several challenges and limitations in terms of validation, interoperability, initial high implementation costs, ethics and transparency in AI and equity in healthcare. DP and AI are essential pillars of modern dermatopathology, with a high necessity of standardization, regulation and a multidisciplinary approach.

摘要

近年来,数字病理学(DP)和人工智能(AI)发展迅猛,尤其在病理学领域,对皮肤病理学的关注度颇高。在新冠疫情的推动下,DP和AI如今已融入病理学、研究及教育之中,为组织病理学诊断、远程病理学及个性化医疗带来了价值。本叙述性综述通过科学计量分析,界定了三个研究方向,对病理学和皮肤病理学中DP和AI的现状进行了全面的文献综述。该研究通过PubMed和Web of Science数据库进行,研究时间段为2019年1月至2025年7月,采用两阶段方法。四名独立病理学家根据纳入和排除标准筛选文章,文章的综合基于三个研究方向。研究表明,卷积神经网络(CNN)、人工智能驱动的诊断平台和远程病理学对提高诊断速度和准确性有很大贡献,尤其是对皮肤恶性肿瘤。在人工智能的验证、互操作性、初始高实施成本、伦理和透明度以及医疗保健公平性方面,仍存在一些挑战和限制。DP和AI是现代皮肤病理学的重要支柱,高度需要标准化、监管和多学科方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8862/12428701/468e46c4eca2/diagnostics-15-02196-g001.jpg

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