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来自(罗尔夫)梅里尔的生物活性天然产物的药理学概述

Pharmacological Overview of Bioactive Natural Products from (Lour.) Merr.

作者信息

Bose Ponkti Addrita, Sohag Md Mehadi Hasan, Rabbee Muhammad Fazle, Zamee Tareque Muzahid, Kona Jab-Un-Nisha, Elora Bonhi, Zaki Randa Mohammed, Islam Kamrul, Baek Kwang-Hyun

机构信息

Department of Genetic Engineering and Biotechnology, Jagannath University, Dhaka 1100, Bangladesh.

Biotechnology Research Initiative for Sustainable Development, Dhaka 1219, Bangladesh.

出版信息

Plants (Basel). 2025 Sep 1;14(17):2714. doi: 10.3390/plants14172714.

Abstract

is a commonly adopted medicinal plant native to the tropical regions of East and Southeast Asia and is well recognized for its significant therapeutic potential. Traditionally used in herbal medicine, it has been employed to manage various conditions, including hypertension, diabetes, renal disorders, constipation, and inflammation. Its leaves are particularly rich in flavonoids-such as astragalin, kaempferol, quercetin, myricetin, and rutin-which are associated with anti-glycaemic, anticancer, antihypertensive, antimicrobial, and antioxidant activities. These bioactive constituents form the basis of the broad pharmacological profile of the plant. Emerging studies also suggest a potential role for in the management of infertility, further broadening its therapeutic scope. This review provides a concise overview of its phytochemical constituents, taxonomic classification, and current pharmacological evidence, highlighting its potential as a valuable candidate for novel drug development.

摘要

是一种常见的药用植物,原产于东亚和东南亚的热带地区,因其具有显著的治疗潜力而广为人知。传统上用于草药医学,它被用于治疗各种病症,包括高血压、糖尿病、肾脏疾病、便秘和炎症。其叶子特别富含黄酮类化合物,如紫云英苷、山奈酚、槲皮素、杨梅素和芦丁,这些化合物具有抗血糖、抗癌、抗高血压、抗菌和抗氧化活性。这些生物活性成分构成了该植物广泛药理特性的基础。新兴研究还表明其在不孕症管理中可能发挥作用,进一步拓宽了其治疗范围。本综述简要概述了其植物化学成分、分类学分类和当前的药理证据,突出了其作为新型药物开发有价值候选物的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77df/12430178/1002c7d5f636/plants-14-02714-g001.jpg

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