Oshima Y, Okaichi H
Shinrigaku Kenkyu. 1985 Oct;56(4):241-4. doi: 10.4992/jjpsy.56.241.
Hippocampectomized (N = 19) and control (N = 18) rats were trained on an elevated T-maze in which place, cue and response strategies employed could be separated from one another. For nine hippocampals and nine controls, a place task was followed by a cue task (place-cue condition) while the order was reversed for the remaining subjects (cue-place condition). The effects of hippocampal lesions on acquisition and transfer of place and cue learning were assessed in terms of correct responses and strategies used by the rats. In both training conditions, performance of hippocampals was significantly impaired for the place task but not for the cue task. Hippocampals used a cue strategy in the cue task but employed a response strategy in the place task. Controls, on the other hand, used a place strategy in the place task and a cue strategy in the cue task. These results suggest that rats with hippocampal lesions are imparied in their ability to employ a place strategy with the result that other strategies are adopted in a place task situation.
对海马切除的大鼠（N = 19）和对照大鼠（N = 18）进行高架T迷宫训练，在该迷宫中，所采用的位置、线索和反应策略可以相互分离。对于9只海马切除大鼠和9只对照大鼠，先进行位置任务，然后进行线索任务（位置 - 线索条件），而其余大鼠的顺序则相反（线索 - 位置条件）。根据大鼠的正确反应和所采用的策略，评估海马损伤对位置和线索学习的习得及迁移的影响。在两种训练条件下，海马切除大鼠在位置任务中的表现显著受损，但在线索任务中未受损。海马切除大鼠在线索任务中采用线索策略，但在位置任务中采用反应策略。另一方面，对照大鼠在位置任务中采用位置策略，在线索任务中采用线索策略。这些结果表明，海马损伤的大鼠运用位置策略的能力受损，结果在位置任务情境中采用了其他策略。
