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一款符合移动性和电磁辐射标准的脑部正电子发射断层扫描(PET)扫描仪的设计。

Design of a Mobile and Electromagnetic Emissions-Compliant Brain Positron Emission Tomography (PET) Scanner.

作者信息

Fuentes Cristian, Béguin Marina, Commichau Volker, Flock Judith, Lomax Anthony J, Makkar Shubhangi, McNamara Keegan, Prior John O, Ritzer Christian, Winterhalter Carla, Dissertori Günther

机构信息

Institute for Particle Physics and Astrophysics, ETH Zurich, 8093 Zurich, Switzerland.

Center for Proton Therapy, PSI, 5232 Villigen, Switzerland.

出版信息

Sensors (Basel). 2025 Aug 28;25(17):5344. doi: 10.3390/s25175344.

Abstract

This paper presents the development of two mobile brain Positron Emission Tomography (PET) scanners under the PETITION project, designed for Intensive Care Units (ICUs) and Proton Beam Therapy (PBT) applications. The ICU scanner facilitates bedside imaging for critically ill patients, while the PBT scanner enables undisturbed proton beam irradiation during imaging. Key aspects of the hardware design, including modular detectors and electromagnetic interference considerations, are discussed along with preliminary performance evaluations. Operational testing, employing a Na source and a hot-rod phantom, was conducted to determine the timing resolution (548 ps), energy resolution (11.4%) and a qualitative spatial resolution (around 2.2 mm). Our study presents findings on the ICU PET scanner's electromagnetic emissions measured in a controlled EMC testing facility, where all the emissions tests performed comply with the standard EN 60601-1-2 (radiated emissions 15 dB below regulatory limits in the frequency range of 30 MHz to 1 GHz).

摘要

本文介绍了在PETITION项目下开发的两款移动式脑正电子发射断层扫描(PET)扫描仪,它们专为重症监护病房(ICU)和质子束治疗(PBT)应用而设计。ICU扫描仪便于对重症患者进行床边成像,而PBT扫描仪能够在成像过程中实现无干扰的质子束照射。文中讨论了硬件设计的关键方面,包括模块化探测器和电磁干扰方面的考虑因素,并进行了初步性能评估。使用钠源和热棒体模进行了操作测试,以确定时间分辨率(548皮秒)、能量分辨率(11.4%)和定性空间分辨率(约2.2毫米)。我们的研究展示了在受控电磁兼容性(EMC)测试设施中对ICU PET扫描仪电磁辐射的测量结果,其中进行的所有辐射测试均符合标准EN 60601-1-2(在30兆赫至1吉赫频率范围内,辐射发射比监管限值低15分贝)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba96/12431185/0b0b88edafcc/sensors-25-05344-g001.jpg

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