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轻度新冠肺炎感染一年后:医护人员存在情绪困扰但认知功能保持良好

One Year After Mild COVID-19: Emotional Distress but Preserved Cognition in Healthcare Workers.

作者信息

Peláez Irene, Martínez-Íñigo David, Fernandes-Magalhaes Roberto, De Lahoz María E, Del Pino Ana Belén, Pérez-Aranda Sonia, García-Romero Alejandro, Soldic Dino, Mercado Francisco

机构信息

Department of Psychology, School of Health Sciences, Rey Juan Carlos University, 28922 Madrid, Spain.

Research Group in Cognitive Neuroscience, Pain and Rehabilitation (NECODOR), Rey Juan Carlos University, 28922 Alcorcón, Spain.

出版信息

J Clin Med. 2025 Aug 25;14(17):6007. doi: 10.3390/jcm14176007.

Abstract

Although COVID-19 may cause cognitive impairments for up to six months, the long-term effects of mild cases remain unclear. Given their high exposure and critical role in public health, assessing this impact on healthcare workers is essential. Aim: The present study aimed to examine the cognitive and emotional effects of mild COVID-19 in 92 healthcare workers one year after infection. : In total, 50 had experienced mild COVID-19, while 42 had not been infected. Participants completed a neuropsychological assessment evaluating attention, memory, and executive functions, along with self-reported measures of anxiety, depression, post-traumatic stress, occupational stress, and burnout. : No significant cognitive differences were observed between the groups. However, both exhibited moderate-to-severe psychological distress, with the COVID-19 group showing higher trait anxiety ( = 0.032). Emotional symptoms were significantly associated with neuropsychological performance-higher burnout (ρ from -0.20 to -0.28, < 0.05) and stress (ρ from -0.25 to -0.33, < 0.01) correlated with slower responses and more errors in tasks such as the D2 variation index, TESEN execution speed, Rey-Osterrieth Figure recall, and Digit Span forward span. : These findings suggest no long-term cognitive impairment after mild COVID-19 but highlight the substantial emotional toll of the pandemic on healthcare workers. Future research should explore cognitive reserve as a protective factor.

摘要

虽然新冠病毒感染可能会导致长达六个月的认知障碍,但轻症病例的长期影响仍不明确。鉴于医护人员面临的高暴露风险及其在公共卫生中的关键作用,评估新冠病毒感染对他们的影响至关重要。目的:本研究旨在调查92名医护人员在感染新冠病毒一年后,轻症感染对其认知和情绪的影响。方法:总共有50人曾感染轻症新冠病毒,42人未被感染。参与者完成了一项神经心理学评估,评估注意力、记忆力和执行功能,同时还进行了焦虑、抑郁、创伤后应激、职业压力和倦怠的自我报告测量。结果:两组之间未观察到显著的认知差异。然而,两组均表现出中度至重度的心理困扰,新冠病毒感染组的特质焦虑水平更高(P = 0.032)。情绪症状与神经心理学表现显著相关——更高的倦怠感(相关系数ρ从 -0.20至 -0.28,P < 0.05)和压力感(相关系数ρ从 -0.25至 -0.33,P < 0.01)与D2变异指数、TESEN执行速度、雷-奥斯特里思复杂图形回忆和数字广度顺背等任务中的反应变慢和错误增多相关。结论:这些发现表明,轻症新冠病毒感染后没有长期的认知障碍,但突出了疫情对医护人员造成的巨大情绪负担。未来的研究应探索认知储备作为一种保护因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a49/12428925/2e21777a244b/jcm-14-06007-g001.jpg

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