Hernandez-Martinez Jordan, Branco Braulio Henrique Magnani, Vasquez-Carrasco Edgar, Cid-Calfucura Izham, Herrera-Valenzuela Tomás, Guzmán-Muñoz Eduardo, Delgado-Floody Pedro, Concha-Cisternas Yeny, Valdés-Badilla Pablo
Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno 5290000, Chile.
Department of Education, Faculty of Humanities, Universidad de la Serena, La Serena 1700000, Chile.
Nutrients. 2025 Sep 2;17(17):2852. doi: 10.3390/nu17172852.
this systematic review with a meta-analysis aimed to evaluate the available body of published peer-reviewed randomized controlled trial (RCT) studies on the effects of different doses and types of strength training (ST) on body composition, physical performance, and protein or calcium intake in older people with osteosarcopenia. a systematic literature search was conducted between July 2024 and August 2025 using five databases: PubMed, Medline, CINAHL Complete, Scopus, and Web of Science. PRISMA, TESTEX, RoB 2, and GRADE tools assessed methodological quality and certainty of evidence. Hedge's g effect sizes were calculated for the abovementioned variables for the meta-analysis. the protocol was registered in PROSPERO (code: CRD42025643858). Of 141 registers, seven RCTs with 349 participants were included. Seven overall and two subgroup meta-analyses showed significant increases in skeletal muscle mass index (SMMI; < 0.01), maximal isometric handgrip strength (MIHS; = 0.03), and protein intake ( = 0.03). There were no significant differences in bone mineral density (BMD), body fat percentage (BFP), gait speed, and calcium intake. However, meta-analysis by subgroups showed significant decreases in BFP = 0.01) in favor of elastic band training versus resistance training, with no significant differences in BMD. ST in older people with osteosarcopenia conditions increases SMMI, MIHS, and protein intake.
这项带有荟萃分析的系统评价旨在评估已发表的、经同行评审的随机对照试验（RCT）研究的现有文献，这些研究涉及不同剂量和类型的力量训练（ST）对患有骨质疏松性肌少症的老年人身体成分、身体机能以及蛋白质或钙摄入量的影响。在2024年7月至2025年8月期间，使用五个数据库进行了系统的文献检索：PubMed、Medline、CINAHL Complete、Scopus和Web of Science。PRISMA、TESTEX、RoB 2和GRADE工具评估了方法学质量和证据的确定性。为荟萃分析计算了上述变量的Hedge's g效应量。该方案已在PROSPERO中注册（代码：CRD42025643858）。在141项注册研究中，纳入了7项RCT，共349名参与者。七项总体和两项亚组荟萃分析显示，骨骼肌质量指数（SMMI；<0.01）、最大等长握力（MIHS；=0.03）和蛋白质摄入量（=0.03）显著增加。骨密度（BMD）、体脂百分比（BFP）、步速和钙摄入量没有显著差异。然而，亚组荟萃分析显示，与阻力训练相比，弹力带训练使BFP显著降低（=0.01），而BMD没有显著差异。患有骨质疏松性肌少症的老年人进行力量训练可增加SMMI、MIHS和蛋白质摄入量。
