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应用胸膜瓣和聚合物密封剂胸腔镜下闭合肺泡胸膜瘘

Thoracoscopic Closure of Alveolar Pleural Fistula by Application of Pleural Flap and Polymeric Sealant.

作者信息

Fiorelli Alfonso, Giorgiano Noemi Maria, Iovine Angela, Tamburrino Antonella, Messina Gaetana

机构信息

Thoracic Surgery Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.

Anesthesiology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.

出版信息

Thorac Cancer. 2025 Sep;16(17):e70156. doi: 10.1111/1759-7714.70156.

Abstract

Persistent air leaks due to alveolar pleural fistula following lung resection were a frustrating clinical condition for patients and clinicians, associated with a prolonged hospital stay and increased morbidity. Several surgical strategies have been reported over the years for the closure of alveolar fistula, but the best treatment was still debated. Herein, we reported the clinical case of a patient who experienced a persistent air leak due to alveolar-pleural fistula following thoracoscopic right upper lobectomy for the management of early lung cancer. The fistula was successfully closed by thoracoscopic application of a pleural flap and polymeric sealant. Our new strategy could turn out to be useful for surgeons when standard procedures for management of APF were unfeasible or difficult to perform. Obviously, our impression should be validated by future large studies in a prospective manner.

摘要

肺切除术后因肺泡胸膜瘘导致的持续性漏气,对患者和临床医生来说都是一种令人沮丧的临床情况,与住院时间延长和发病率增加相关。多年来已报道了几种用于闭合肺泡瘘的手术策略,但最佳治疗方法仍存在争议。在此,我们报告了一例因早期肺癌行胸腔镜右上叶切除术后因肺泡胸膜瘘导致持续性漏气的患者的临床病例。通过胸腔镜应用胸膜瓣和聚合物密封剂成功闭合了瘘口。当处理肺泡胸膜瘘的标准程序不可行或难以实施时,我们的新策略可能对外科医生有用。显然,我们的观点应通过未来前瞻性的大型研究来验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7f2/12432017/e2b5b1d93e94/TCA-16-e70156-g003.jpg

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