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双极导管消融术作为成功治疗心室内膜心律失常的关键:双极-基尔研究结果

Bipolar Catheter Ablation as a Key for Successful Treatment of Intramural VentricuLar Arrhythmias: Results From the Bipolar-Kiel Study.

作者信息

Moser Fabian, Maslova Vera, Zaman Adrian, Demming Thomas, Spehlmann Martina, Saad Mohammed, Frank Derk, Lian Evgeny

机构信息

Department of Cardiology and Internal Intensive Medicine, University Hospital Schleswig Holstein, Kiel, Germany.

出版信息

J Cardiovasc Electrophysiol. 2025 Sep 14. doi: 10.1111/jce.70018.

Abstract

BACKGROUND

Unipolar catheter ablation (CA) is effective in the treatment of ventricular arrhythmias but its efficacy can be limited in eliminating intramural arrhythmic origins. Bipolar ablation has emerged as a bail-out strategy. However, currently, it is being primarily utilized after a failed ablation attempt.

OBJECTIVE

The aim of this study is to assess the safety and efficacy of endocardial and/or epicardial bipolar catheter ablation in patients with ventricular arrhythmias within their first procedure or after a previously failed ablation attempt.

METHODS AND RESULTS

Patients who underwent bipolar CA between September 2022 and February 2025 were included. A total of 21 bipolar ablation procedures were performed in 19 patients (median age 66 ± 11, 11% female, median ejection fraction 42% ± 16%). In total, 16 procedures were performed due to ventricular tachycardia (VT) or VT storm, five procedures were performed due to symptomatic premature ventricular contractions (PVC). In 48% of all cases, ablation was performed within the patient's first procedure. The interventricular septum was the most common site of bipolar ablation (11/21), followed by epi-endocardial bipolar ablation procedures (9/21) and the papillary muscle (1/21). Bipolar ablation was successful in 17/21 patients. In one patient, AV block occurred after bipolar ablation. During a median follow-up time of 12 ± 6 months, four patients with initially acute procedural success experienced recurrence of a ventricular arrhythmia.

CONCLUSION

Bipolar catheter ablation is an effective tool for arrhythmias with an intramural origin. It is shown to be safe with a high acute success rate in patients undergoing their first or redo procedure for VT or PVC.

摘要

背景

单极导管消融术(CA)在治疗室性心律失常方面有效,但在消除壁内心律失常起源方面其疗效可能有限。双极消融已成为一种补救策略。然而,目前它主要在消融尝试失败后使用。

目的

本研究的目的是评估心内膜和/或心外膜双极导管消融术在首次手术或先前消融尝试失败的室性心律失常患者中的安全性和有效性。

方法和结果

纳入了2022年9月至2025年2月期间接受双极CA的患者。19例患者共进行了21次双极消融手术(中位年龄66±11岁,女性占11%,中位射血分数42%±16%)。总共16例手术是由于室性心动过速(VT)或VT风暴进行的,5例手术是由于有症状的室性早搏(PVC)进行的。在所有病例的48%中,消融是在患者的首次手术中进行的。室间隔是双极消融最常见的部位(11/21),其次是心外膜 - 心内膜双极消融手术(9/21)和乳头肌(1/21)。双极消融在17/21例患者中成功。1例患者在双极消融后发生了房室传导阻滞。在中位随访时间12±6个月期间,4例最初手术成功的患者出现了室性心律失常复发。

结论

双极导管消融是治疗壁内起源心律失常的有效工具。在因VT或PVC接受首次或再次手术的患者中,它被证明是安全的,急性成功率高。

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