Malatji Nompumelelo, Mpupa Anele, Mizaikoff Boris, Nomngongo Philiswa Nosizo
Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, PO Box 17011, 2028 Doornfontein, South Africa.
Department of Science and Innovation-National Research Foundation South African Research Chair Initiative (DSI-NRF SARChI) in Nanotechnology for Water, University of Johannesburg, 2028 Doornfontein, South Africa.
iScience. 2025 Jul 24;28(8):113205. doi: 10.1016/j.isci.2025.113205. eCollection 2025 Aug 15.
The association of PFOA with low concentrations and complex water matrices has made its direct quantification using sensitive analytical methods such as UHPLC-ESI-MS/MS challenging. This study used a magnetic beta-cyclodextrin-based molecularly imprinted polymer (TWAC-FeO@β-CD-MIP) prepared via surface imprinting on magnetic tea waste activated carbon (TWAC-FeO). Under optimal conditions, the method exhibited a linear range (17-5000 ng/L, R = 0.9990) in real water, with LOD and LOQ of 8.6 ng/L and 29 ng/L, respectively. Precision was high, with intraday and interday %RSD of 2.1% and 3.7%. The adsorbent was reusable for three cycles while maintaining over 60% recovery. Spike recoveries in water samples ranged from 102 to 106% with %RSD <5%, confirming the method's accuracy. The imprinting factor was 5.57, and adsorption followed the Sips isotherm model. This study explored MIPs for PFOA determination in water.
全氟辛酸（PFOA）与低浓度及复杂水基质的关联使得采用超高效液相色谱-电喷雾串联质谱（UHPLC-ESI-MS/MS）等灵敏分析方法对其进行直接定量具有挑战性。本研究使用了一种基于磁性β-环糊精的分子印迹聚合物（TWAC-FeO@β-CD-MIP），该聚合物通过在磁性茶叶废料活性炭（TWAC-FeO）上进行表面印迹制备而成。在最佳条件下，该方法在实际水样中呈现出线性范围（17 - 5000 ng/L，R = 0.9990），检测限（LOD）和定量限（LOQ）分别为8.6 ng/L和29 ng/L。精密度较高，日内和日间相对标准偏差（%RSD）分别为2.1%和3.7%。该吸附剂可重复使用三个循环，同时回收率保持在60%以上。水样中的加标回收率在102%至106%之间，%RSD <5%，证实了该方法的准确性。印迹因子为5.57，吸附遵循Sips等温线模型。本研究探索了用于测定水中PFOA的分子印迹聚合物。
