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疫情之后:通过世界心脏联盟全球新冠研究探索新冠长期症状对全球健康的影响。

Following the Pandemic: Exploring Long COVID's impact on Global Health through the World Heart Federation Global COVID-19 Study.

作者信息

Santo Karla, Favaro Leandro, Martins Eduardo

机构信息

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

出版信息

Glob Heart. 2025 Sep 12;20(1):79. doi: 10.5334/gh.1468. eCollection 2025.

Abstract

Although the COVID-19 pandemic crisis has come to an end, Long COVID continues to pose a profound challenge to global health. Based on findings from the World Heart Federation (WHF) Global COVID-19 Study, an international prospective cohort study, this editorial reflects on the enduring burden of symptoms and complications among 2,535 previously hospitalized patients across 16 countries during the Omicron era. Beyond a mortality rate of 15% and clinical manifestations such as fatigue, dyspnea, and adverse cardiovascular events, the study highlighted substantial psychosocial and socioeconomic impacts, with reduced work capacity and functional limitations particularly affecting populations in low- and middle-income countries captured through EuroQol 5-dimension scale and employment data. These findings emphasize that the burden of Long COVID extends beyond individual health, with significant implications for healthcare systems and economic stability. Addressing this challenge requires ongoing multidisciplinary research, validated diagnostic criteria, novel biomarkers, and effective preventive and therapeutic strategies. Furthermore, decentralized monitoring models-exemplified by telephone-based data collection in the WHF study-may offer scalable approaches to improve surveillance and inform global health policies for current and future public health crises.

摘要

尽管新冠疫情危机已经结束,但新冠后遗症仍继续对全球健康构成严峻挑战。基于世界心脏联盟(WHF)全球新冠研究(一项国际前瞻性队列研究)的结果,这篇社论反思了在奥密克戎时代,16个国家的2535名曾住院患者中症状和并发症的持续负担。除了15%的死亡率以及疲劳、呼吸困难和不良心血管事件等临床表现外,该研究还突出了重大的心理社会和社会经济影响,通过欧洲五维健康量表和就业数据发现,工作能力下降和功能受限对低收入和中等收入国家的人群影响尤为严重。这些发现强调,新冠后遗症的负担不仅限于个人健康,对医疗系统和经济稳定也有重大影响。应对这一挑战需要持续开展多学科研究、验证诊断标准、寻找新的生物标志物以及制定有效的预防和治疗策略。此外,以WHF研究中基于电话的数据收集为代表的分散监测模式,可能提供可扩展的方法来加强监测,并为当前和未来公共卫生危机的全球卫生政策提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2561/12427623/8361923a4d24/gh-20-1-1468-g1.jpg

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