Bindernagel Richard G, Boccardi Aleia, Jindia Taylor C, Patel Parth, Bryan Jaimie, Walker Addie, Moon Summer, Miller Richard
HCA Florida Largo Hospital, Largo, Florida.
John's Episcopal Hospital, Far Rockaway, New York.
HCA Healthc J Med. 2025 Aug 1;6(4):363-366. doi: 10.36518/2689-0216.1974. eCollection 2025.
Endometriosis is a common condition in which endometrial glands and stroma are implanted outside the uterine cavity. Rarely, the skin can be involved.
We describe a case of a 41-year-old woman who presented to the dermatology clinic complaining of a brown umbilical nodule with slight erythema. It was occasionally painful and hemorrhagic. She denied a history of endometriosis and abdominal surgeries. A shave biopsy of the nodule was consistent with a diagnosis of cutaneous endometriosis. The patient was referred to her gynecologist for further evaluation and treatment.
This unique case demonstrates primary cutaneous endometriosis in the umbilicus of a female patient. Cutaneous endometriosis can be classified as primary or secondary. Primary cutaneous endometriosis is rarer and has an unclear etiology, developing seemingly spontaneously without history of surgical interventions. Secondary cutaneous endometriosis typically arises within surgical scars following abdominal operations, which is believed to be a result of iatrogenic implantation of endometrial cells. Definitive treatment involves surgery. This case highlights the importance of considering cutaneous endometriosis in the differential diagnosis of a female patient with painful and intermittently hemorrhagic skin nodules.
子宫内膜异位症是一种常见病症，其中子宫内膜腺体和间质植入子宫腔外。皮肤受累的情况较为罕见。
我们描述了一例41岁女性患者，她到皮肤科诊所就诊，主诉脐部有一个伴有轻微红斑的褐色结节。该结节偶尔疼痛且出血。她否认有子宫内膜异位症和腹部手术史。对该结节进行削切活检，结果符合皮肤子宫内膜异位症的诊断。患者被转介给妇科医生进行进一步评估和治疗。
这一独特病例显示了一名女性患者脐部的原发性皮肤子宫内膜异位症。皮肤子宫内膜异位症可分为原发性或继发性。原发性皮肤子宫内膜异位症较为罕见，病因不明，似乎是在无手术干预史的情况下自发发生的。继发性皮肤子宫内膜异位症通常出现在腹部手术后的手术瘢痕内，据信这是子宫内膜细胞医源性植入的结果。明确的治疗方法是手术。该病例凸显了在对有疼痛和间歇性出血性皮肤结节的女性患者进行鉴别诊断时考虑皮肤子宫内膜异位症的重要性。
