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重度二尖瓣狭窄合并肺动脉高压的妊娠患者行再次剖宫产的围手术期管理:体外膜肺氧合备用的作用

Perioperative Management of a Pregnant Patient With Severe Mitral Stenosis and Pulmonary Hypertension for Repeat Cesarean Section: The Role of Standby Extracorporeal Membrane Oxygenation.

作者信息

Kachhwaha Avaish, Karagyozyan Daniela S, Aluzri Nadia, Vandse Rashmi

机构信息

Anesthesiology and Perioperative Medicine, Loma Linda University Medical Center, Loma Linda, USA.

Anesthesiology and Perioperative Medicine, Loma Linda University School of Medicine, Loma Linda, USA.

出版信息

Cureus. 2025 Aug 13;17(8):e89986. doi: 10.7759/cureus.89986. eCollection 2025 Aug.

DOI:10.7759/cureus.89986
PMID:40951122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12428160/
Abstract

Managing pregnant patients with severe mitral stenosis (MS) and pulmonary hypertension (PH) remains a challenge, requiring a multidisciplinary approach to mitigate maternal and fetal risks. We report a case of a 29-year-old female, gravida 6 para 5, at 37 weeks' gestation with severe rheumatic MS, significant PH, and right ventricular (RV) dysfunction who underwent an elective repeat cesarean delivery. Due to her elevated risk of hemodynamic collapse, invasive monitoring, incremental epidural anesthesia, and standby extracorporeal membrane oxygenation (ECMO) were utilized. Intraoperative vasopressor and uterotonic selection was optimized to maintain systemic perfusion while minimizing pulmonary vascular resistance. The procedure was successfully completed without complications, with close inpatient monitoring post-partum; both maternal and neonatal outcomes were favorable. This case highlights the value of detailed perioperative preparation, multidisciplinary coordination, and personalized anesthetic and pharmacologic management in pregnancies complicated by severe cardiac disease.

摘要

管理患有严重二尖瓣狭窄(MS)和肺动脉高压(PH)的孕妇仍然是一项挑战,需要多学科方法来降低母婴风险。我们报告一例29岁女性病例,孕6产5,妊娠37周,患有严重风湿性MS、显著PH和右心室(RV)功能障碍,接受了择期再次剖宫产。由于她发生血流动力学崩溃的风险升高,因此采用了有创监测、逐步增加的硬膜外麻醉和备用体外膜肺氧合(ECMO)。术中优化了血管升压药和宫缩剂的选择,以维持全身灌注,同时尽量降低肺血管阻力。手术顺利完成,无并发症,产后进行了密切的住院监测;母婴结局均良好。该病例凸显了在合并严重心脏疾病的妊娠中,详细的围手术期准备、多学科协调以及个性化麻醉和药物管理的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6134/12428160/998b3a9ed011/cureus-0017-00000089986-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6134/12428160/998b3a9ed011/cureus-0017-00000089986-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6134/12428160/998b3a9ed011/cureus-0017-00000089986-i01.jpg

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A review of the effects of Valsalva manoeuvre in labour and birth.瓦尔萨尔瓦动作对分娩过程影响的综述。
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