School of Rehabilitation Medicine, Weifang Medical University, 7166 Baotong West Street, Weifang, Shandong, China.
School of Medical, Shanghai University, 99 Shangda Road, Shanghai, China.
Dysphagia. 2023 Feb;38(1):145-158. doi: 10.1007/s00455-022-10486-6. Epub 2022 Jul 18.
The Eating Assessment Tool-10 (EAT-10) is used worldwide to screen people quickly and easily at high risk for swallowing disorders. However, the best EAT-10 cutoff value is still controversial. In this systematic review and meta-analysis, we estimated and compared the diagnostic accuracy of EAT-10 cutoff values of 2 and 3 for screening dysphagia. We searched the PubMed, Web of Science, EMBASE, Cochrane Library, CNKI, WANFANG, and VIP databases from May 2008 to March 2022. The meta-analysis included 7 studies involving 1064 subjects from 7 different countries. Two studies were classified as high quality and five studies as medium quality. With an EAT-10 cutoff value of 2, using flexible endoscopic evaluation of swallowing or video fluoroscopic swallowing study as the gold standard, the pooled sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio were 0.89 (95% confidence interval [CI] 0.82-0.93), 0.59 (95% CI 0.39-0.77), 2.17 (95% CI 1.38-3.42), 0.19 (95% CI 0.13-0.29), and 11.49 (95% CI 5.86-22.53), respectively. When a cutoff of 3 was used, these values were 0.85 (95% CI 0.68-0.94), 0.82 (95% CI 0.65-0.92), 4.84 (95% CI 1.72-13.50), 0.18 (95% CI 0.07-0.46), and 26.24 (95% CI 5.06-135.95), respectively. Using EAT-10 cutoff values of 2 and 3, the areas under the curve were 0.873 (95% CI 0.82-0.93) and 0.903 (95% CI 0.88-0.93), respectively, showing good diagnostic performance. EAT-10 can be used as a preliminary screening tool for dysphagia. However, a cutoff of 3 is recommended for EAT-10 due to better diagnostic accuracy.
《进食评估量表-10（EAT-10）》被广泛用于快速、简便地筛查吞咽障碍高风险人群。然而，最佳的 EAT-10 截断值仍存在争议。本系统评价和荟萃分析旨在评估和比较 EAT-10 截断值为 2 和 3 时筛查吞咽困难的诊断准确性。我们检索了 2008 年 5 月至 2022 年 3 月期间 PubMed、Web of Science、EMBASE、Cochrane 图书馆、CNKI、WANFANG 和 VIP 数据库。荟萃分析纳入了来自 7 个不同国家的 7 项研究，共 1064 名受试者。其中 2 项研究被归类为高质量，5 项研究为中等质量。使用灵活的内镜吞咽评估或视频荧光透视吞咽研究作为金标准，EAT-10 截断值为 2 时，汇总的敏感度、特异度、阳性似然比、阴性似然比和诊断比值比分别为 0.89（95%置信区间 [CI] 0.82-0.93）、0.59（95% CI 0.39-0.77）、2.17（95% CI 1.38-3.42）、0.19（95% CI 0.13-0.29）和 11.49（95% CI 5.86-22.53）。当截断值为 3 时，这些值分别为 0.85（95% CI 0.68-0.94）、0.82（95% CI 0.65-0.92）、4.84（95% CI 1.72-13.50）、0.18（95% CI 0.07-0.46）和 26.24（95% CI 5.06-135.95）。使用 EAT-10 截断值 2 和 3 时，曲线下面积分别为 0.873（95% CI 0.82-0.93）和 0.903（95% CI 0.88-0.93），具有良好的诊断性能。EAT-10 可作为吞咽困难的初步筛查工具。然而，由于诊断准确性更高，建议 EAT-10 的截断值为 3。
