Selamoglu Z, Dogan H, Naeem M Y, Ozdemir B, Issa H Y, Akgul H
Department of Medical Biology, Faculty of Medicine, Nigde Omer Halisdemir University, Nigde, Turkey.
Western Caspian University, Baku, Azerbaijan.
Arch Razi Inst. 2025 Feb 1;80(1):69-73. doi: 10.32592/ARI.2025.80.1.69. eCollection 2025 Feb.
Honeybees produce propolis by collecting resinous material from various plant parts, such as buds, sap flows, leaves, and bark. It is used in traditional medicine and health services due to its biological activity. The content of propolis affects by their geographical and botanical origins and changes in their contents cause changes in their biological effects. Turkey has a rich structure in geography, ecology and climate because it incorporates three different floristic areas in country. These different structures have led to a variety of plants that vary from region to region. Propolis samples for this study were collected from 11 regions across Turkey, including Artvin, Duzce, and Balikesir. Antioxidant measurements were made on propolis samples extracted with a specific method. Total oxidant status and oxidative index were calculated by in vitro analysis, and then compared. The in vitro analyses were performed using newly developed research measurement kits that were extremely sensitive and reliable. In the results of this study, antioxidant capacity has been linked to phenolic compounds. Statistical significance was determined to each propolis samples in different regions. As a result, the total antioxidant capacity of propolis was highest in the Artvin region (P<0.01). Antioxidant and oxidant capacities and oxidative stress indices of propolis samples of different regions were determined statistically. This research includes in vitro assays that include highly reliable tests based on very useful and precise measurements. In Turkey variable characteristics of the region were monitored. For this reason, differences were observed in the total antioxidant capacities of propolis samples by region. Honeybees produce propolis, a natural resinous substance, by collecting it from various plant parts, such as buds, sap flows, leaves, and bark. This substance has found application in traditional medicine and health services due to its biological activity. The chemical composition of propolis varies depending on its geographical and botanical origins, with alterations in the constituent components resulting in corresponding changes in biological effects. Turkey's unique geographical, ecological, and climatic characteristics are attributable to the presence of three distinct floristic regions within its borders. The diversity of these regions is reflected in the variety of plant species found in each area. For the present study, propolis samples were collected from 11 regions across Turkey, including Artvin, Duzce, and Balikesir. Antioxidant measurements were made on propolis samples extracted using a specific method. The antioxidant status and oxidative index of the samples were calculated using in vitro analysis and subsequently compared. The in vitro analyses were performed using research measurement kits that were newly developed and characterized by extreme sensitivity and reliability. The study's findings suggest a correlation between antioxidant capacity and phenolic compounds. Statistical significance was determined for each propolis sample from different regions. The Artvin region was found to have the highest total antioxidant capacity of the propolis samples (P<0.01). The study further examined the antioxidant and oxidant capacities, along with oxidative stress indices, of propolis samples from diverse regions. The research encompasses in vitro assays, incorporating highly reliable tests based on precise measurements. The study also monitored the variable characteristics of the region in Turkey. Consequently, variations in the total antioxidant capacities of propolis samples by region were observed.
蜜蜂通过从各种植物部位收集树脂状物质来生产蜂胶，这些植物部位包括芽、树液流动处、叶子和树皮。由于其生物活性，蜂胶被用于传统医学和健康服务中。蜂胶的成分受其地理和植物来源的影响，其成分的变化会导致其生物效应的改变。土耳其在地理、生态和气候方面具有丰富的结构，因为其国内包含三个不同的植物区系。这些不同的结构导致了不同地区植物种类的多样性。本研究的蜂胶样本采集自土耳其的11个地区，包括阿尔特温、杜兹和巴勒克埃西尔。采用特定方法对提取的蜂胶样本进行抗氧化测量。通过体外分析计算总氧化剂状态和氧化指数，然后进行比较。体外分析使用新开发的研究测量试剂盒进行，这些试剂盒极其灵敏且可靠。在本研究结果中，抗氧化能力与酚类化合物有关。确定了不同地区每个蜂胶样本的统计学显著性。结果，阿尔特温地区的蜂胶总抗氧化能力最高（P<0.01）。对不同地区蜂胶样本的抗氧化和氧化能力以及氧化应激指数进行了统计学测定。本研究包括体外试验，这些试验包括基于非常有用和精确测量的高度可靠的测试。在土耳其监测了该地区的可变特征。因此，观察到不同地区蜂胶样本的总抗氧化能力存在差异。蜜蜂通过从芽、树液流动处、叶子和树皮等各种植物部位收集蜂胶这种天然树脂状物质来生产它。由于其生物活性，这种物质已在传统医学和健康服务中得到应用。蜂胶的化学成分因其地理和植物来源而异，组成成分的改变会导致生物效应相应变化。土耳其独特的地理、生态和气候特征归因于其境内存在三个不同的植物区系。这些地区的多样性反映在每个地区发现的植物物种的多样性上。对于本研究，从土耳其的11个地区收集了蜂胶样本，包括阿尔特温、杜兹和巴勒克埃西尔。采用特定方法对提取的蜂胶样本进行抗氧化测量。使用体外分析计算样本的抗氧化状态和氧化指数，随后进行比较。体外分析使用新开发的研究测量试剂盒进行，这些试剂盒的特点是极其灵敏和可靠。该研究的结果表明抗氧化能力与酚类化合物之间存在相关性。确定了来自不同地区的每个蜂胶样本的统计学显著性。发现阿尔特温地区的蜂胶样本总抗氧化能力最高（P<0.01）。该研究进一步检查了来自不同地区的蜂胶样本的抗氧化和氧化能力以及氧化应激指数。该研究包括体外试验，包括基于精确测量的高度可靠的测试。该研究还监测了土耳其该地区的可变特征。因此，观察到不同地区蜂胶样本的总抗氧化能力存在差异。
