Hosseinpour Aghaei B, Taiefi Nasrabadi N, Pirali Y, Shojaei S S
Department of pathobiology, Karaj branch, Islamic Azad University, Karaj, Iran.
Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
Arch Razi Inst. 2025 Feb 1;80(1):263-269. doi: 10.32592/ARI.2025.80.1.263. eCollection 2025 Feb.
Fasciolosis, a foodborne parasitic disease, is caused by the trematodes Fasciola hepatica and Fasciola gigantica. This disease is of significant concern, having been reported in various vertebrate hosts across more than 80 countries. A comparison of the geographical distribution of the two species reveals that Fasciola hepatica affects a wider range of animals and is often reported from high altitudes and hot and humid areas. The present study endeavors to provide an update on fascioliasis in animal and human hosts in Iran during the years 2019 to 2024. A systematic search of published articles in English was conducted using electronic databases including Google Scholar, PubMed, Iran Science Direct, SID and Magiran. Following a thorough review of the literature, a total of 18 articles were identified that satisfied the predetermined inclusion criteria for the evaluation of the prevalence of fascioliasis in humans and animals within the Iranian context. Of the 18 articles that were subjected to analysis, only five documented the presence of the Fasciola hepatica species. In four articles, researchers encountered difficulties in identifying the specific species of Fasciola. Notably, the remaining articles reported the presence of both F. hepatica and F. gigantica species. The molecular analysis was employed in 61.1% of the cases, which is noteworthy. The prevalence of human fascioliasis exhibited variability, ranging from 1.7% to 2.4% across diverse regions of Iran. The present systematic review revealed that there has been a paucity of studies conducted in the field of fasciolosis in Iran during the last five years. Consequently, the authors of the present study recommend the implementation of further research focusing on the prevalence of fasciolosis in all provinces. The authors further recommend the formulation and dissemination of effective prevention and control strategies for this disease, contingent on the prevalence of fasciolosis in different provinces.
肝片吸虫病是一种食源性寄生虫病，由肝片吸虫和巨片吸虫这两种吸虫引起。这种疾病备受关注，已在80多个国家的各种脊椎动物宿主中被报道。对这两个物种地理分布的比较表明，肝片吸虫影响的动物种类范围更广，且经常在高海拔以及炎热潮湿地区被报道。本研究致力于提供2019年至2024年期间伊朗动物和人类宿主中肝片吸虫病的最新情况。使用包括谷歌学术、PubMed、伊朗科学直接数据库、SID和Magiran在内的电子数据库，对已发表的英文文章进行了系统检索。在对文献进行全面审查后，共确定了18篇符合预定纳入标准的文章，用于评估伊朗境内人类和动物肝片吸虫病的流行情况。在接受分析的18篇文章中，只有5篇记录了肝片吸虫物种的存在。在4篇文章中，研究人员在鉴定肝片吸虫的特定物种时遇到了困难。值得注意的是，其余文章报告了肝片吸虫和巨片吸虫这两个物种均存在。61.1%的病例采用了分子分析，这一点值得注意。伊朗不同地区人类肝片吸虫病的流行率呈现出差异，范围在1.7%至2.4%之间。本系统综述表明，在过去五年中，伊朗肝片吸虫病领域的研究较少。因此，本研究的作者建议开展进一步研究，重点关注所有省份肝片吸虫病的流行情况。作者还建议根据不同省份肝片吸虫病的流行情况，制定并传播针对该疾病的有效预防和控制策略。
