Addressing the evidence gap: exploratory insights into dual challenges of mild cognitive impairment and hematologic cancer in older adults through mixed methods and social listening study.

PURPOSE

The ageing European population faces a dual burden of increasing mild cognitive impairment (MCI) and hematologic malignancies, yet the overlap of these conditions remains poorly understood and insufficiently addressed in current research and clinical practice. This study aims to explore the unmet needs and challenges encountered by older adults living with both MCI and hematologic malignancies, to inform the development of integrated, person-centered care models for this raising population.

METHODS

A mixed-methods approach was employed, combining a systematic literature review (2018-2023) with qualitative social listening from publicly available caregiver and patient platforms. Screening followed PRISMA guidelines; posts were analyzed thematically using NVivo software.

RESULTS

The systematic review found no eligible studies addressing the dual diagnosis, reflecting a substantial evidence gap. Social listening identified two dominant themes: (1) persistent feelings of isolation among patients and (2) significant emotional and logistical burden on caregivers. Both findings emphasize the disconnect between current care models and patient realities.

CONCLUSION

Older adults with coexisting MCI and hematologic malignancies represent a neglected and highly vulnerable population. The lack of dedicated research and integrated care highlights an urgent need for new clinical frameworks and tools that better account for cognitive health in geriatric oncology. Future research should focus on developing and validating brief, sensitive cognitive screening tools, training clinicians in cognitively-informed oncology care, and designing multidisciplinary support systems for patients and caregivers navigating dual diagnoses.