Brabin B J
Trans R Soc Trop Med Hyg. 1985;79(5):652-6. doi: 10.1016/0035-9203(85)90182-8.
Folacin deficiency in malaria endemic areas is not reported other than in severely malnourished children. This is surprising in view of the high incidence in these areas of malaria in pregnancy, with its complications of prematurity and low birth weight, all of which can predispose to folacin deficiency. This paper reports results of folacin and cobalamin activities of blood samples collected from women at parturition and their newborns in a holoendemic area in West Kenya. Evidence is given that Plasmodium falciparum infection has little influence on cord plasma or red cell folacin activities. Mean values for folacin and cobalamin are not low when compared with reported values from neonates from temperate climates.
除了严重营养不良的儿童外，疟疾流行地区未报告有叶酸缺乏的情况。鉴于这些地区妊娠疟疾的高发病率及其早产和低出生体重并发症，所有这些都可能导致叶酸缺乏，这一现象令人惊讶。本文报告了在肯尼亚西部一个高度流行地区收集的产妇及其新生儿血液样本的叶酸和钴胺素活性结果。有证据表明，恶性疟原虫感染对脐血血浆或红细胞叶酸活性影响很小。与温带气候地区新生儿的报告值相比，叶酸和钴胺素的平均值并不低。
