Case Report: vertebral osteomyelitis in a pigeon breeder: mNGS diagnosis of chronic Q fever.

BACKGROUND

Isolated vertebral osteomyelitis represents an uncommon manifestation of chronic Q fever, posing significant diagnostic challenges. We report a case of -induced spondylodiscitis confirmed via metagenomic next-generation sequencing (mNGS).

CASE REPORT

A 52-year-old male with occupational avian exposure (pigeon breeder) presented with chronic low back pain persisting for over 1 year, refractory to serial epidural corticosteroid injections. Lumbar MRI demonstrated multifocal osteomyelitis (L3-L5) with associated intraspinal abscess. mNGS analysis of aspirate identified . Targeted dual antimicrobial therapy (vancomycin/doxycycline) induced progressive clinical resolution.

CONCLUSION

, the etiological agent of Q fever, exhibits global distribution and poses significant diagnostic challenges. Its clinical manifestations are frequently nonspecific, typically afebrile, and diagnosis is commonly delayed by months to years post-symptom onset. mNGS offers critical diagnostic utility for early identification and therapeutic intervention in rare spinal infections, thereby mitigating complication risks.