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跨越颈椎平面的结石痕迹:广泛双侧颈胸钙化酷似侵袭性病变。

Stone Trails Across the Cervical Planes: Extensive Bilateral Cervicothoracic Calcifications Mimicking Invasive Pathology.

作者信息

Rashid Humna, Sohail Hadia, Younus Muhammad, Khurshied Saleh, Faatmaa Syeda Hoorya

机构信息

Otolaryngology - Head and Neck Surgery, Pakistan Institute of Medical Sciences, Islamabad, PAK.

出版信息

Cureus. 2025 Aug 17;17(8):e90308. doi: 10.7759/cureus.90308. eCollection 2025 Aug.

DOI:10.7759/cureus.90308
PMID:40964545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12440238/
Abstract

Benign soft tissue calcifications in the neck are uncommon and can pose significant diagnostic challenges due to their clinical and radiological resemblance to malignant lesions. It is crucial to distinguish between these entities in order to prevent unnecessary and aggressive interventions. We describe the case of a 38-year-old woman who had an anterior neck swelling that had been painful, firm, and irregular for four years and had no previous comorbidities. With no accompanying symptoms like dysphagia, dyspnea, or voice abnormalities, the mass had an abrupt onset and did not progress. A fixed, firm swelling that moved with deglutition and tongue protrusion was discovered during the clinical examination. Imaging revealed widespread, pleomorphic calcifications extending from the cervical to the upper thoracic area. These extended transfascially and transcompartmentally, with a modest mass effect on nearby structures. Ultrasound-guided FNAC was non-diagnostic, and a subsequent incisional biopsy revealed calcified and fibrous tissue without evidence of malignancy. Since there were no compressive symptoms and the histology was benign, the patient was treated conservatively and monitored closely. This case emphasizes how crucial it is to perform a thorough clinical, radiographic, and histological investigation in order to differentiate benign calcified neck masses from malignancies. Conservative management with close monitoring may be appropriate in selected cases without compressive or systemic signs.

摘要

颈部良性软组织钙化并不常见,由于其在临床和影像学上与恶性病变相似,可能会带来重大的诊断挑战。区分这些病变实体至关重要,以避免不必要的激进干预。我们描述了一名38岁女性的病例,她颈部前方肿胀已有四年,疼痛、质地坚硬且形状不规则,既往无合并症。该肿块起病突然,无吞咽困难、呼吸困难或声音异常等伴随症状,且无进展。临床检查发现一个固定、坚硬的肿胀,随吞咽和伸舌活动。影像学检查显示广泛的多形性钙化,从颈部延伸至上胸部区域。这些钙化跨筋膜和跨间隙延伸,对附近结构有轻微的占位效应。超声引导下细针穿刺抽吸活检(FNAC)未得出诊断结果,随后的切开活检显示为钙化和纤维组织,无恶性证据。由于没有压迫症状且组织学检查为良性,该患者接受了保守治疗并密切监测。该病例强调了进行全面的临床、影像学和组织学检查以区分颈部良性钙化肿块与恶性肿瘤的重要性。在没有压迫或全身症状的特定病例中,密切监测下的保守治疗可能是合适的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/dfa5da44c3d0/cureus-0017-00000090308-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/bc9a55589160/cureus-0017-00000090308-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/14c47c489bb8/cureus-0017-00000090308-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/b17ecb3aa512/cureus-0017-00000090308-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/52bf906c34b5/cureus-0017-00000090308-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/dfa5da44c3d0/cureus-0017-00000090308-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/bc9a55589160/cureus-0017-00000090308-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/14c47c489bb8/cureus-0017-00000090308-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/b17ecb3aa512/cureus-0017-00000090308-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/52bf906c34b5/cureus-0017-00000090308-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9c/12440238/dfa5da44c3d0/cureus-0017-00000090308-i05.jpg

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本文引用的文献

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Ear Nose Throat J. 2023 Nov 22:1455613231213493. doi: 10.1177/01455613231213493.
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Anaplastic Thyroid Carcinoma Mimicking Cervical Tuberculosis: A Case Report.模仿颈部结核的间变性甲状腺癌:一例报告
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Prevalence and Radiographic Features of Head and Neck Soft Tissue Calcifications on Digital Panoramic Radiographs: A Retrospective Study.
数字化全景X线片上头颈部软组织钙化的患病率及影像学特征:一项回顾性研究
Cureus. 2023 Sep 26;15(9):e46025. doi: 10.7759/cureus.46025. eCollection 2023 Sep.
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Imaging features of cartilaginous tumors of the head and neck.头颈部软骨肿瘤的影像学特征。
J Clin Imaging Sci. 2021 Dec 4;11:66. doi: 10.25259/JCIS_186_2021. eCollection 2021.
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Soft tissue calcifications: a pictorial essay.软组织钙化:图文综述
Radiol Bras. 2020 Sep-Oct;53(5):337-344. doi: 10.1590/0100-3984.2019.0100.
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Laryngeal Chondrosarcoma of the Thyroid Cartilage.喉软骨肉瘤。
Turk Patoloji Derg. 2021;37(2):178-182. doi: 10.5146/tjpath.2020.01509.
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Calcifying Fibrous Tumor of the Neck.颈部钙化性纤维瘤。
Head Neck Pathol. 2020 Jun;14(2):507-511. doi: 10.1007/s12105-019-01100-7. Epub 2019 Nov 28.
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