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ICANS and mortality after CAR-T therapy for NHL patients can be predicted using physical function measures of falls, balance and strength deficits, and use of an assistive device.

作者信息

Nair Nisha M, Hahn Theresa E, Jacobson Hillary, Holtan Shernan, Davila Marco L, McCarthy Philip L, Betts Brian Christopher, Ross Maureen, Ray Andrew, McKenzie Renee, Schofield Grant, Malek Ehsan, Herr Megan M

机构信息

Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Cancer Prevention & Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

出版信息

Bone Marrow Transplant. 2025 Sep 18. doi: 10.1038/s41409-025-02714-y.

DOI:10.1038/s41409-025-02714-y
PMID:40968178
Abstract
摘要

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ICANS and mortality after CAR-T therapy for NHL patients can be predicted using physical function measures of falls, balance and strength deficits, and use of an assistive device.
Bone Marrow Transplant. 2025 Sep 18. doi: 10.1038/s41409-025-02714-y.
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本文引用的文献

1
Baseline Serum Inflammatory Proteins Predict Poor CAR T Outcomes in Diffuse Large B-cell Lymphoma.基线血清炎症蛋白预测弥漫性大 B 细胞淋巴瘤中嵌合抗原受体 T 细胞治疗结局不良。
Blood Cancer Discov. 2024 Mar 1;5(2):106-113. doi: 10.1158/2643-3230.BCD-23-0056.
2
Physical function, nutritional status, and quality of life before and after chemotherapy in patients with malignant lymphoma.恶性淋巴瘤患者化疗前后的身体功能、营养状况和生活质量。
Medicine (Baltimore). 2023 Feb 10;102(6):e32901. doi: 10.1097/MD.0000000000032901.
3
CAR-HEMATOTOX: a model for CAR T-cell-related hematologic toxicity in relapsed/refractory large B-cell lymphoma.
嵌合抗原受体 T 细胞相关血液学毒性:复发/难治性大 B 细胞淋巴瘤中嵌合抗原受体 T 细胞相关血液学毒性的模型。
Blood. 2021 Dec 16;138(24):2499-2513. doi: 10.1182/blood.2020010543.
4
Association of Balance Function With All-Cause and Cause-Specific Mortality Among US Adults.美国成年人的平衡功能与全因和特定原因死亡率的关系。
JAMA Otolaryngol Head Neck Surg. 2021 May 1;147(5):460-468. doi: 10.1001/jamaoto.2021.0057.
5
Association Between Muscular Strength and Mortality in Clinical Populations: A Systematic Review and Meta-Analysis.肌肉力量与临床人群死亡率的关系:系统评价和荟萃分析。
J Am Med Dir Assoc. 2019 Oct;20(10):1213-1223. doi: 10.1016/j.jamda.2019.05.015. Epub 2019 Jul 19.
6
Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies.血液系统恶性肿瘤老年患者的步态速度、握力和临床结局。
Blood. 2019 Jul 25;134(4):374-382. doi: 10.1182/blood.2019000758. Epub 2019 Jun 5.