Ichihashi M, Hasei K, Horikawa T
Br J Dermatol. 1985 Dec;113(6):745-50. doi: 10.1111/j.1365-2133.1985.tb02411.x.
Photobiological tests were carried out on a 32-year-old man who suffered from porphyria cutanea tarda (PCT). The patient developed an immediate type of skin reaction with erythema and whealing following monochromatic irradiation at 400 nm, but did not have any abnormal immediate skin reaction after exposure to natural sunlight. Pre- or simultaneous irradiation with visible light, wavelength greater than 650 nm, suppressed the development of urticaria induced by 400 nm monochromatic radiation. On the basis of these findings and our previous observation of an inhibitory spectrum in two cases of solar urticaria, we suggest that there is also an inhibitory spectrum in PCT. This could explain the extremely low incidence of immediate erythematous or urticarial reactions in sun-exposed skin in these patients.
对一名患有迟发性皮肤卟啉症（PCT）的32岁男性进行了光生物学测试。该患者在400nm单色照射后出现了伴有红斑和风团的速发型皮肤反应，但暴露于自然阳光下后未出现任何异常的速发型皮肤反应。用波长大于650nm的可见光进行预照射或同时照射，可抑制400nm单色辐射诱发的荨麻疹的发生。基于这些发现以及我们之前在两例日光性荨麻疹中观察到的抑制光谱，我们认为PCT中也存在抑制光谱。这可以解释这些患者暴露于阳光下的皮肤中速发性红斑或荨麻疹反应的发生率极低的原因。
