Liu Xiao, Zhou Huadi, Yang Xiaohu, Wang Zhen
The Fourth Clinical Medical School of Zhejiang Chinese Medical University Hangzhou Zhejiang China.
Zhejiang Hospital Hangzhou Zhejiang China.
RSC Adv. 2025 Sep 17;15(41):33962-33965. doi: 10.1039/d5ra05436b.
A radical cascade cyclization of aryl ynones with alkyl halides was established to synthesise alkylated indenones in yields of 43 to 83% under metal- and oxidant-free and room temperature conditions. The approach enables the construction of two C-C bonds through a XAT process using BuN as XAT catalyst.
建立了芳基炔酮与卤代烃的自由基串联环化反应，在无金属、无氧化剂及室温条件下合成烷基化茚满酮，产率为43%至83%。该方法能够通过使用BuN作为XAT催化剂的XAT过程构建两个C-C键。
