Kumar Shishir, Panchal Mrunalkant, Mishra Pranay, Srivastava Preeti, Tanti Sanjay K
Department of Surgery, Tata Main Hospital, Jamshedpur, IND.
Department of Surgery, Manipal Tata Medical College, Manipal Academy of Higher Education, Jamshedpur, IND.
Cureus. 2025 Aug 18;17(8):e90370. doi: 10.7759/cureus.90370. eCollection 2025 Aug.
Background Meckel's diverticulum (MD) is a congenital anomaly of the gastrointestinal tract characterized as a true diverticulum that contains all three layers of the intestinal wall. It is typically situated on the antimesenteric border of the terminal ileum and receives blood supply from the vitelline artery. Although often asymptomatic, MD can lead to complications such as intestinal obstruction, gastrointestinal bleeding, perforation with peritonitis, and, rarely, malignancy. Histologically, ectopic gastric and pancreatic tissues are the most commonly observed findings. Methods This retrospective study reviewed pediatric cases of symptomatic MD treated between June 2022 and May 2025. Data regarding clinical presentation, operative procedures, histopathological findings, and treatment outcomes were analyzed. Results The average age at presentation was 40 months, ranging from one to 60 months. Among the six children studied, two (33%) presented with umbilical discharge, and two (33%) had intestinal obstruction, one (16%) of whom had associated bowel gangrene. These four (64%) patients underwent laparotomy with ileal resection and anastomosis. One (16%) child presented with perforation peritonitis due to a ruptured MD and required an emergency ileostomy, later reversed after eight months. One (16%) child, who had intermittent lower gastrointestinal bleeding and anemia, underwent laparoscopy-assisted Meckel's diverticulectomy. Histopathology revealed ectopic gastric mucosa in five (84%) patients and pancreatic tissue in one (16%) patient; no malignancy was identified. Conclusion Prompt surgical resection with restoration of bowel continuity is crucial in cases of symptomatic MD. Although resection of incidentally discovered MD during unrelated abdominal procedures is sometimes considered due to its potential for future complications, including bleeding or malignancy, there is currently insufficient evidence to support the routine removal of asymptomatic MD in the absence of other abdominal pathology.
梅克尔憩室(MD)是胃肠道的一种先天性异常,其特征为含有肠壁全层的真性憩室。它通常位于回肠末端的肠系膜对侧缘,由卵黄管动脉供血。虽然MD通常无症状,但可导致肠梗阻、胃肠道出血、穿孔伴腹膜炎等并发症,恶性肿瘤则较为罕见。组织学上,最常见的发现是异位胃和胰腺组织。方法:本回顾性研究对2022年6月至2025年5月期间治疗的有症状MD患儿病例进行了回顾。分析了临床表现、手术操作、组织病理学发现和治疗结果等数据。结果:就诊时的平均年龄为40个月,范围为1至60个月。在研究的6名儿童中,2名(33%)出现脐部排液,2名(33%)患有肠梗阻,其中1名(16%)伴有肠坏疽。这4名(64%)患者接受了剖腹探查术并行回肠切除吻合术。1名(16%)儿童因MD破裂出现穿孔性腹膜炎,需要紧急行回肠造口术,8个月后恢复。1名(16%)有间歇性下消化道出血和贫血的儿童接受了腹腔镜辅助梅克尔憩室切除术。组织病理学显示,5名(84%)患者有异位胃黏膜,1名(16%)患者有胰腺组织;未发现恶性肿瘤。结论:对于有症状的MD病例,及时进行手术切除并恢复肠道连续性至关重要。尽管在无关腹部手术中偶然发现的MD有时因其未来可能出现包括出血或恶性肿瘤等并发症而被考虑切除,但目前尚无足够证据支持在无其他腹部病变的情况下常规切除无症状的MD。