Moreno Fábia Kariny Mendes, Rodrigues Gabriel Menezes, Martinez Victor Otero, Barreto Cinthia Oliveira de Araujo, Silva Laís Pereira, Fontes Thanielle Novaes, Barbosa Vivian Fernanda, da Costa-Neto João Moreira, Estrela-Lima Alessandra
Research Center on Mammary Oncology (NPqOM), Federal University of Bahia, Salvador, Brazil.
Department of Veterinary Anatomy, Pathology and Clinics, School of Veterinary Medicine and Zootechny, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.
PLoS One. 2025 Sep 19;20(9):e0332598. doi: 10.1371/journal.pone.0332598. eCollection 2025.
Surgical wound closure is critical in oncologic surgeries and directly influences healing, postoperative complications, and recovery time. In canine mastectomies, conventional skin closure with nylon sutures remains the standard technique; however, surgical staples have emerged as a potential alternative that can potentially optimize surgical efficiency and outcomes. This study evaluated the efficacy of surgical staples as an alternative to routine standard suture (nylon) in female dogs undergoing mastectomies. Fifty female dogs were divided into two groups: one was treated with nylon suture (NS group, n = 25) and the other with surgical staples (SS group, n = 25). Surgical time, local wound temperature, and wound healing characteristics were evaluated. Thermographic analysis of the surgical scar was performed on a subsample. Logistic regression and multivariate linear analysis were used to compare differences between the techniques, and an independent samples t test was applied to compare surgical and suture times. No significant differences were found between the groups regarding age, weight, incision size, body size, and reproductive status. Total surgical time was significantly shorter in the SS group (p = 0.011). The closure time was 9.8 times shorter in the SS group versus the NS group (p < 0.001). The average wound temperature was higher in the NS group (p < 0.001). The SS group showed fewer occurrences of wound alterations (p = 0.029) and a lower frequency of focal inflammatory exudate (p = 0.013). The thermographic analysis showed more white pixels and higher temperatures in the surgical wound in the NS group versus the SS group (p = 0.032 and p < 0.001, respectively). Surgical staples were found to be safe and effective for wound closure in mastectomies in female dogs, offering a viable alternative to traditional nylon suture techniques. Although the cost of staples is slightly higher, the benefits of shorter surgical time and reduced complications can make this technique a favorable choice, especially for oncologic patients with additional health concerns or surgical time restrictions.
手术伤口闭合在肿瘤手术中至关重要，直接影响愈合、术后并发症和恢复时间。在犬类乳房切除术中，使用尼龙缝线进行传统皮肤闭合仍是标准技术；然而，手术吻合钉已成为一种潜在的替代方法，有可能优化手术效率和结果。本研究评估了手术吻合钉作为常规标准缝线（尼龙）的替代方法，用于接受乳房切除术的雌性犬的疗效。50只雌性犬分为两组：一组用尼龙缝线治疗（NS组，n = 25），另一组用手术吻合钉治疗（SS组，n = 25）。评估了手术时间、局部伤口温度和伤口愈合特征。对一个子样本进行了手术瘢痕的热成像分析。使用逻辑回归和多元线性分析来比较技术之间的差异，并应用独立样本t检验来比较手术时间和缝合时间。两组在年龄、体重、切口大小、体型和生殖状态方面未发现显著差异。SS组的总手术时间明显更短（p = 0.011）。SS组的闭合时间比NS组短9.8倍（p < 0.001）。NS组的平均伤口温度更高（p < 0.001）。SS组伤口改变的发生率更低（p = 0.029），局灶性炎性渗出物的频率更低（p = 0.013）。热成像分析显示，NS组手术伤口中的白色像素更多、温度更高，而SS组则相反（分别为p = 0.032和p < 0.001）。研究发现，手术吻合钉用于雌性犬乳房切除术的伤口闭合安全有效，是传统尼龙缝线技术的可行替代方法。尽管吻合钉的成本略高，但手术时间缩短和并发症减少的益处使该技术成为一个有利的选择，特别是对于有其他健康问题或手术时间限制的肿瘤患者。
