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Incidence and Risk Factors of Pulmonary Complications Following Femur Fracture Surgery in Patients Aged 80 Years and Older.80 岁及以上股骨骨折手术患者肺部并发症的发生率及危险因素。
Clin Interv Aging. 2024 Nov 7;19:1843-1854. doi: 10.2147/CIA.S481641. eCollection 2024.
3
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain.猪模型中的股骨钉固定术会导致肺部出现骨髓栓子以及心脏和脑部出现全身栓子。
JB JS Open Access. 2024 Feb 28;9(1). doi: 10.2106/JBJS.OA.23.00128. eCollection 2024 Jan-Mar.
4
Comparing short vs. intermediate and long nails in elderly patients with unstable multifragmental femoral trochanteric fractures (AO type A2): Multicenter (TRON group) retrospective study.比较不稳定的老年股骨转子间粉碎性骨折(AO 分型 A2)患者的短钉与中长钉:多中心(TRON 组)回顾性研究。
Injury. 2024 Apr;55(4):111420. doi: 10.1016/j.injury.2024.111420. Epub 2024 Feb 10.
5
Does the Level and Complexity of Femur Fracture Determine Intramedullary Peak Pressures During Reamed Femoral Nailing? A Prospective Study.股骨骨折的程度和复杂性是否会影响扩髓髓内钉固定术中的髓内峰值压力?一项前瞻性研究。
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老年股骨转子间骨折使用长髓内钉治疗时肺部并发症风险增加:881例患者的回顾性研究

Increased Risk of Pulmonary Complications with Long Cephalomedullary Nails in Geriatric Intertrochanteric Femur Fractures: A Retrospective Review of 881 Patients.

作者信息

Muhammad Maaz, Green Griffin, Southall Wyatt G S, Musick Adam N, Gregg Austin T, Wagner Robert K, Hawk Gregory S, Aneja Arun

机构信息

Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.

Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Lexington, Kentucky.

出版信息

JB JS Open Access. 2025 Sep 19;10(3). doi: 10.2106/JBJS.OA.25.00170. eCollection 2025 Jul-Sep.

DOI:10.2106/JBJS.OA.25.00170
PMID:40978003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12443157/
Abstract

BACKGROUND

Despite extensive literature comparing short and long cephalomedullary nails (CMNs), the impact of CMN length on pulmonary complications in geriatric patients with intertrochanteric (IT) fractures is not well established. This study compared postoperative pulmonary complications in geriatric patients with IT fractures treated with short (<235 mm) or intermediate (235-240 mm) CMNs (SINs) versus long (≥300 mm) CMNs (LNs).

METHODS

Patients aged ≥65 years with AO Foundation/Orthopaedic Trauma Association (AO/OTA) 31A1-A3 fractures treated with SINs or LNs between 2008 and 2020 were retrospectively identified at a single Level 1 Trauma center. The primary outcome was inpatient postoperative pulmonary complications. Secondary outcomes included mortality, surgical duration, and other inpatient postoperative complications. Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were calculated using logistic regression to adjust for comorbidities (i.e., diabetes, hypertension, chronic) obstructive pulmonary disease, smoking status, age, AO/OTA classification, ASA ≥3, time to surgery, and surgical duration.

RESULTS

Overall, 881 patients were treated with either an SIN (n = 327) or an LN (n = 554). The SIN group was older (80.7 ± 9.1 years vs. 79.3 ± 8.4 years, p = 0.016), had a higher proportion of AO/OTA 31A1 fractures (p < 0.001), and included more patients with ASA ≥3 (89% vs. 84%, p = 0.035). In the SIN group, the median surgical duration was shorter (60 [interquartile range (IQR): 47-79] vs. 81 minutes [IQR: 62-106], p < 0.001), and rates of postoperative anemia (74% vs. 81%, p = 0.017) and transfusion (43% vs. 54%, p = 0.001) were lower. After adjusting for covariates, multivariable analysis demonstrated increased odds of postoperative pneumonia (AOR: 2.09, 95% CI: 1.01-4.71, p = 0.048), pulmonary embolism (AOR: 4.38, 95% CI: 1.09-29.5, p = 0.036), and transfusion (AOR: 1.38, 95% CI: 1.02-1.85, p = 0.034) in the LN group. There were no differences in mortality or other postoperative complications (p > 0.05).

CONCLUSIONS

Geriatric patients with IT fractures treated with LNs had increased odds of inpatient postoperative pneumonia, pulmonary embolism, and transfusion. However, mortality and other postoperative complications were similar.

LEVEL OF EVIDENCE

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

尽管有大量文献比较了短和长的股骨近端髓内钉(CMN),但CMN长度对老年转子间(IT)骨折患者肺部并发症的影响尚未明确。本研究比较了接受短(<235 mm)或中(235 - 240 mm)CMN(SIN)与长(≥300 mm)CMN(LN)治疗的老年IT骨折患者的术后肺部并发症。

方法

在一家一级创伤中心对2008年至2020年间接受SIN或LN治疗的年龄≥65岁的AO基金会/骨科创伤协会(AO/OTA)31A1 - A3骨折患者进行回顾性识别。主要结局是住院术后肺部并发症。次要结局包括死亡率、手术时间和其他住院术后并发症。使用逻辑回归计算调整后的优势比(AOR)及95%置信区间(CI),以调整合并症(即糖尿病、高血压、慢性阻塞性肺疾病、吸烟状况、年龄、AO/OTA分类、ASA≥3、手术时间和手术时长)。

结果

总体而言,881例患者接受了SIN(n = 327)或LN(n = 554)治疗。SIN组患者年龄更大(80.7±9.1岁 vs. 79.3±8.4岁,p = 0.016),AO/OTA 31A1骨折比例更高(p < 0.001),且ASA≥3的患者更多(89% vs. 84%,p = 0.035)。SIN组的中位手术时间更短(60[四分位间距(IQR):47 - 79] vs. 81分钟[IQR:62 - 106],p < 0.001),术后贫血(74% vs. 81%,p = 0.017)和输血率(43% vs. 54%,p = 0.001)更低。在调整协变量后,多变量分析显示LN组术后肺炎(AOR:2.09,95%CI:1.01 - 4.71,p = 0.048)、肺栓塞(AOR:4.38,95%CI:1.09 - 29.5,p = 0.036)和输血(AOR:1.38,95%CI:1.02 - 1.85,p = 0.034)的优势比增加。死亡率或其他术后并发症无差异(p > 0.05)。

结论

接受LN治疗的老年IT骨折患者术后发生肺炎、肺栓塞和输血的几率增加。然而,死亡率和其他术后并发症相似。

证据水平

治疗性三级。有关证据水平的完整描述,请参阅作者指南。