da Costa Daniella Socci, Vianna Raul N G, Moraes Remo Turchetti, Dos Passos Junior Gilberto, Gameiro Filho Aluisio Rosa
Instituto Brasileiro de Oftalmologia (IBOL), Rio de Janeiro, Brazil.
Hospital Federal dos Servidores do Estado (HFSE), Rio de Janeiro, Brazil.
Am J Ophthalmol Case Rep. 2025 Sep 2;40:102418. doi: 10.1016/j.ajoc.2025.102418. eCollection 2025 Dec.
To report a case of a 11-year-old girl, who developed a bilateral acute macular neuroretinopathy (AMN) after Epstein-Barr virus (EBV) encephalitis.
Clinical findings and multimodal imaging including fundus photography, near-infrared reflectance, spectral-domain, and enhanced-deep imaging optical coherence tomography (OCT) of a patient with bilateral acute macular neuroretinopathy after Epstein-Barr virus encephalitis.
After conducting a literature review in August 2024 using PubMed and Google Scholar, using the keywords "acute macular neuroretinopathy", "AMN", "Epstein-Barr", "Epstein-Barr virus", "EBV", "encephalitis" "Epstein-Barr encephalitis" "EBV encephalitis" we did not find any previous reports of AMN associated with EBV encephalitis, such as in our case. Near infrared imaging and spectral-domain optical coherence tomography are key diagnostic tools for this condition, even when fundoscopic findings are subtle.
报告一例11岁女孩，在感染爱泼斯坦-巴尔病毒（EBV）脑炎后发生双侧急性黄斑神经视网膜病变（AMN）。
对一名爱泼斯坦-巴尔病毒脑炎后双侧急性黄斑神经视网膜病变患者的临床发现及多模态成像，包括眼底照相、近红外反射、光谱域和增强深度成像光学相干断层扫描（OCT）。
2024年8月使用PubMed和谷歌学术进行文献综述，关键词为“急性黄斑神经视网膜病变”“AMN”“爱泼斯坦-巴尔”“爱泼斯坦-巴尔病毒”“EBV”“脑炎”“爱泼斯坦-巴尔脑炎”“EBV脑炎”，我们未发现此前有与EBV脑炎相关的AMN报道，如我们的病例。即使眼底镜检查结果不明显，近红外成像和光谱域光学相干断层扫描也是诊断这种疾病的关键工具。
